SCHEMBL3408448

SCHEMBL3408448

CCc1cc(O[C@]2(O)C(O)O[C@H](CO)[C@@H](O)[C@@H]2O)c2c(CCc3ccc4c(c3)CCO4)n[nH]c2c1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 14/20 0.56
▸ SLC5A1 P13866 9/20 0.44
▸ CHRM5 P08912 6/20 0.32
▸ CHRM1 P11229 6/20 0.32
▸ CHRM4 P08173 2/20 0.32
▸ CHRM3 P20309 2/20 0.32
▸ CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3407835 1.00 SLC5A2 (0.56) SLC5A2SLC5A1CHRM5CHRM1CHRM4
SCHEMBL3407836 1.00 SLC5A2 (0.56) SLC5A2SLC5A1CHRM5CHRM1CHRM4
SCHEMBL3406446 0.92 SLC5A2 (0.55) SLC5A2SLC5A1CHRM5CHRM1CHRM4
SCHEMBL3406449 0.92 SLC5A2 (0.55) SLC5A2SLC5A1CHRM5CHRM1CHRM4
SCHEMBL4423504 0.85 SLC5A2 (0.75) SLC5A2SLC5A1
SCHEMBL3414167 0.85 SLC5A2 (0.51) SLC5A2SLC5A1
SCHEMBL3414169 0.85 SLC5A2 (0.51) SLC5A2SLC5A1
SCHEMBL3411735 0.83 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL3407831 0.83 SLC5A2 (0.57) SLC5A2SLC5A1CHRM5CHRM1CHRM4
SCHEMBL3408444 0.83 SLC5A2 (0.57) SLC5A2SLC5A1CHRM5CHRM1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816331-B2 Substituted indazole-O-glucosides JANSSEN PHARMACEUTICA NV (BE) 2010-10-19 — — US disclosed
US-20100062971-A1 SUBSTITUTED INDAZOLE-O-GLUCOSIDES PATEL MONA 2010-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062971-A1 SUBSTITUTED INDAZOLE-O-GLUCOSIDES GYS2, GPR119, UGGT1 SLC5A2 10/4885SLC5A1 9/4885CHRM5 2983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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