Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372948 | 0.83 | ALDH1A1 (0.44) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| SCHEMBL1275171 | 0.82 | SNCA (0.47) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| Butanol SCHEMBL7695797 | 0.82 | ALDH1A1 (0.46) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| Butanol SCHEMBL7695800 | 0.82 | ALDH1A1 (0.46) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| Isopropyl Alcohol SCHEMBL143707 | 0.82 | GAA (0.52) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| SCHEMBL11027526 | 0.82 | GAA (0.52) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| SCHEMBL8462068 | 0.82 | GAA (0.52) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| SCHEMBL593976 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2C19CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL8178505 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 | |
| SCHEMBL28110139 | 0.80 | CA2 (0.42) | CYP1A2CYP2C19CYP2D6CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8422202-B2 | Capacitor and method for manufacturing the same | SHIN-ETSU POLYMER CO., LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20110051323-A1 | CAPACITOR AND METHOD FOR MANUFACTURING THE SAME | SHIN-ETSU POLYMER CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20100182734-A1 | CAPACITOR AND PRODUCTION METHOD THEREOF | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-07-22 | — | — | US | disclosed |