SCHEMBL3408610

SCHEMBL3408610

Cn1nc(Oc2ncc(S(=O)(=O)O)s2)cc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
GAA P10253 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.33
SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3414853 0.76 PKM (0.44) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL4050889 0.69 PKM (0.56) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL3413010 0.69 PKM (0.41) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL2633819 0.69 GAA (0.67) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL3410199 0.68 PKM (0.45) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL6529529 0.67 PKM (0.47) PKMNPC1RAB9AMAPTMEN1
SCHEMBL1153683 0.66 PKM (0.46) PKMGAAL3MBTL1NPC1RAB9A
SCHEMBL3382600 0.65 PKM (0.57) PKMGAANPC1RAB9AMAPT
SCHEMBL20798394 0.65 PKM (1.00) PKMNPC1RAB9AMAPTMEN1
SCHEMBL25399055 0.64 PKM (0.60) PKMGAAL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262794-A1 SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE BASF SE (DE) 2010-12-22 EP disclosed
US-20100317516-A1 Sulfonamide Compounds And Their Use As Fungicide BASF SE (DE) 2010-12-16 US disclosed
WO-2009103650-A1 SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE BASF SE (DE) 2009-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317516-A1 Sulfonamide Compounds And Their Use As Fungicide STS, ARSA, CYP4X1 PKM 2018/4885GAA 1886/4885L3MBTL1 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.