Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507122 | 0.77 | KMT2A (0.50) | KDM4EPOLBRAB9AMEN1KMT2A | |
| SCHEMBL1832494 | 0.77 | PKM (0.43) | PKMKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL9474164 | 0.73 | PKM (0.45) | PKMKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL13530471 | 0.72 | PKM (0.44) | PKMRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL8111889 | 0.72 | PKM (0.55) | PKMKDM4EPOLBRAB9AMEN1 | |
| SCHEMBL3382600 | 0.70 | PKM (0.57) | PKMKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL13098615 | 0.70 | KEAP1 (0.47) | PKMKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL5227374 | 0.69 | POLB (0.45) | PKMKDM4EPOLBMEN1KMT2A | |
| SCHEMBL16612787 | 0.69 | PKM (0.49) | PKMRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8932318 | 0.69 | PKM (0.43) | PKMKDM4ERAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |