⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358932 | 0.98 | MMP1 (0.40) | — | |
| SCHEMBL9285990 | 0.82 | — | — | |
| SCHEMBL11518456 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL13500189 | 0.78 | MMP2 (0.49) | — | |
| SCHEMBL10290203 | 0.76 | CHRNB2 (0.36) | — | |
| SCHEMBL24122291 | 0.76 | — | — | |
| SCHEMBL13112976 | 0.76 | GRIK1 (0.38) | — | |
| SCHEMBL22792570 | 0.76 | — | — | |
| SCHEMBL13494846 | 0.76 | MMP2 (0.37) | — | |
| SCHEMBL2527358 | 0.75 | GRIK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689714-A | Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom | 庄臣及庄臣视力保护公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109790353-A | SILICONE HYDROGELS COMPRISING POLYAMIDES | 庄臣及庄臣视力保护公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790243-A | Three block prepolymer and its purposes in silicone hydrogels | 庄臣及庄臣视力保护公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109689714-A | Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom | 庄臣及庄臣视力保护公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109563293-A | Polymer composition containing graft polymers network and it is used to prepare and uses their method | 庄臣及庄臣视力保护公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109415474-A | SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES | 庄臣及庄臣视力保护公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109416414-A | Increased hardness central optic zone in soft contact lenses for astigmatism correction | 庄臣及庄臣视力保护公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-101981471-B | Tinted silicone ophthalmic devices, processes and polymers used in the preparation of same | JOHNSON & JOHNSON VISION CARE | 2015-01-28 | — | — | CN | disclosed |
| EP-2705073-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | Johnson & Johnson Vision Care Inc. (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012151134-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| CN-101981471-A | Tinted silicone ophthalmic devices, processes and polymers used in the preparation of same | JOHNSON & JOHNSON VISION CARE | 2011-02-23 | — | — | CN | disclosed |
| EP-2260335-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | Johnson & Johnson Vision Care, Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124048-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090244479-A1 | TINTED SILICONE OPHTHALMIC DEVICES, PROCESSES AND POLYMERS USED IN THE PREPARATION OF SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2009-10-01 | — | — | US | disclosed |