Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 12/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412257 | 0.95 | L3MBTL3 (0.33) | L3MBTL3MBTD1OPRM1OPRL1OPRK1 | |
| SCHEMBL3405677 | 0.95 | L3MBTL3 (0.33) | L3MBTL3MBTD1OPRM1OPRL1OPRK1 | |
| SCHEMBL3412261 | 0.95 | L3MBTL3 (0.33) | L3MBTL3MBTD1OPRM1OPRL1OPRK1 | |
| SCHEMBL3407790 | 0.85 | CHRM1 (0.37) | L3MBTL3MBTD1OPRM1OPRL1OPRK1 | |
| SCHEMBL3405961 | 0.83 | CHRM1 (0.50) | L3MBTL1 | |
| SCHEMBL3407654 | 0.83 | CHRM2 (0.42) | L3MBTL3MBTD1OPRM1OPRL1OPRK1 | |
| SCHEMBL3410336 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1 | |
| SCHEMBL3410334 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1 | |
| SCHEMBL3410341 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1 | |
| SCHEMBL3412434 | 0.82 | OPRM1 (0.43) | L3MBTL3OPRM1OPRL1OPRK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257543-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | AstraZeneca AB (SE) | 2010-12-08 | — | — | EP | claimed |
| WO-2009108117-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | claimed |