Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412429 | 1.00 | OPRM1 (0.43) | OPRM1OPRL1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL3412436 | 1.00 | OPRM1 (0.43) | OPRM1OPRL1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL3410135 | 0.92 | PDE4B (0.34) | OPRM1OPRL1OPRK1PDE4BPDE4D | |
| SCHEMBL3410138 | 0.92 | PDE4B (0.34) | OPRM1OPRL1OPRK1PDE4BPDE4D | |
| SCHEMBL3407951 | 0.92 | PDE4B (0.34) | OPRM1OPRL1OPRK1PDE4BPDE4D | |
| SCHEMBL3409386 | 0.82 | L3MBTL3 (0.39) | OPRM1OPRL1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL3411318 | 0.82 | OPRL1 (0.47) | OPRM1OPRL1OPRK1CHRM2CHRM1 | |
| SCHEMBL1929548 | 0.79 | OPRM1 (0.46) | OPRM1OPRL1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL3410347 | 0.78 | OPRM1 (0.48) | OPRM1OPRL1OPRK1L3MBTL3L3MBTL1 | |
| SCHEMBL3407790 | 0.78 | CHRM1 (0.37) | OPRM1OPRL1OPRK1L3MBTL3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257543-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | AstraZeneca AB (SE) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009108117-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |
| US-20090221567-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221567-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 | CHRM1, CHRM2, CHRM3 | OPRM1 6/4885OPRL1 7/4885OPRK1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.