Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046410 | 1.00 | MAPT (0.55) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL3974022 | 0.98 | MAPT (0.52) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL4060725 | 0.85 | CNR2 (0.49) | HDAC1HDAC2HDAC3MAPK1ADRA1A | |
| SCHEMBL29792919 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL11294877 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL11291692 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL7102236 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL28554084 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL11288235 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL5511989 | 0.83 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3741381-B1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | UNIV CORNELL (US) | 2024-04-24 | — | — | EP | disclosed |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2023-12-14 | — | — | US | disclosed |
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2023-04-18 | — | — | US | disclosed |
| US-20210023161-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2021-01-28 | — | — | US | disclosed |
| EP-3741381-A1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3243521-B1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | UNIV CORNELL (US) | 2020-05-27 | — | — | EP | disclosed |
| US-20180177840-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| EP-3243521-A1 | A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2262520-B1 | COMPOSITIONS FOR PREVENTION AND TREATMENT OF RENAL INJURY | UNIV CORNELL (US) | 2017-05-03 | — | — | EP | disclosed |
| US-20170112893-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2017-04-27 | — | — | US | disclosed |
| US-8940696-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2015-01-27 | — | — | US | disclosed |
| US-8592373-B2 | Methods for prevention and treatment of acute renal injury | CORNELL UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130017150-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2013-01-17 | — | — | US | disclosed |
| EP-2262520-A2 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | Cornell University (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20090221514-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY | 2009-09-03 | — | — | US | disclosed |
| WO-2009108695-A2 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | CORNELL UNIVERSITY (US) | 2009-09-03 | — | — | WO | disclosed |
| EP-1024815-B1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | SYMBOLLON CORP (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1024815-A1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | Symbollon Corporation (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021567-A1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION OF MOLECULAR IODINE | SYMBOLLON CORPORATION (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5885592-A | FEEDING MAMMAL IODINE SPECIES OXIDANT AND IODINE REDUCTANT CONTAINING IODINE SPECIES WHICH UNDERGOES OXIDATION-REDUCTION REACTION ON CONTACT WITH GASTRIC JUICE TO GENERATE MOLECULAR IODINE IN VIVO | SYMBOLLON CORPORATION (US) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11628198-B2 | Methods for prevention and treatment of acute renal injury | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20230398172-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20180177840-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20170112893-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20130017150-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20090221514-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
| US-20210023161-A1 | METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY | ARG2, SERPINC1, ARG1 | MAPT 4424/4885RXFP1 25/4885TRPA1 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.