Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407676 | 0.86 | TAS2R14 (0.36) | ATMKDM4EKMT2ATDP1L3MBTL1 | |
| SCHEMBL3403825 | 0.86 | KDM4E (0.33) | ATMKDM4EKMT2ATDP1L3MBTL1 | |
| SCHEMBL3404345 | 0.83 | — | — | |
| SCHEMBL3407823 | 0.83 | ADORA2A (0.39) | ATMKDM4EKMT2ATDP1L3MBTL1 | |
| SCHEMBL3404213 | 0.81 | MAPT (0.35) | ATMKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3407555 | 0.80 | MAPT (0.32) | MAPT | |
| SCHEMBL3404301 | 0.80 | BCHE (0.33) | KDM4EKMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3403318 | 0.80 | — | — | |
| SCHEMBL3403902 | 0.79 | CA2 (0.34) | KDM4EPOLBMAPT | |
| SCHEMBL3405776 | 0.79 | ATM (0.33) | ATMKDM4EKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |