Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403704 | 0.85 | MLYCD (0.34) | MAPT | |
| SCHEMBL3401870 | 0.82 | LMNA (0.34) | — | |
| SCHEMBL3403741 | 0.82 | LDHA (0.32) | — | |
| SCHEMBL3403908 | 0.81 | NPC1 (0.32) | — | |
| SCHEMBL3409999 | 0.80 | ATM (0.34) | MAPT | |
| SCHEMBL3405643 | 0.80 | CA2 (0.33) | MAPT | |
| SCHEMBL3408188 | 0.80 | MAPT (0.39) | MAPT | |
| SCHEMBL3406523 | 0.79 | HDAC8 (0.39) | — | |
| SCHEMBL3405070 | 0.79 | MAPT (0.36) | MAPT | |
| SCHEMBL3406734 | 0.79 | CA2 (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |