Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744876 | 0.88 | GPR84 (0.51) | GPR84SLC5A2SLC5A1CYP2A6FFAR1 | |
| SCHEMBL19216922 | 0.84 | CYP2A6 (0.54) | GPR84CYP2A6FFAR1HTR2AMEN1 | |
| SCHEMBL31415122 | 0.78 | GPR84 (0.50) | GPR84CYP2A6FFAR1HTR2AMEN1 | |
| SCHEMBL16650024 | 0.77 | GPR84 (0.73) | GPR84SLC5A2SLC5A1FFAR1HTR2A | |
| SCHEMBL31744874 | 0.76 | FGFR1 (0.51) | GPR84HTR2AMEN1KMT2AHTR1B | |
| SCHEMBL3411024 | 0.76 | CFTR (0.42) | CYP2A6 | |
| SCHEMBL8542889 | 0.75 | GPR84 (0.45) | GPR84SLC5A2SLC5A1CYP2A6FFAR1 | |
| SCHEMBL147220 | 0.74 | KMT2A (0.74) | GPR84CYP2A6HTR2AMEN1KMT2A | |
| SCHEMBL25381397 | 0.74 | CYP2A6 (0.50) | GPR84CYP2A6FFAR1HTR2AMEN1 | |
| SCHEMBL3478093 | 0.71 | HTR2A (0.68) | GPR84CYP2A6FFAR1HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816328-B2 | Substituted fused heterocyclic C-glycosides | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-19 | — | — | US | disclosed |
| US-20100004160-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | RYBCZYNSKI PHILIP | 2010-01-07 | — | — | US | disclosed |
| US-20090105162-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | RYBCZYNSKI PHILIP | 2009-04-23 | — | — | US | disclosed |
| US-7482330-B2 | Substituted fused heterocyclic C-glycosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-27 | — | — | US | disclosed |
| US-20060229260-A1 | Substituted fused heterocyclic C-glycosides | Tanabe Pharma Corporation (JP) | 2006-10-12 | — | — | US | disclosed |
| US-7094763-B2 | Substituted fused heterocyclic C-glycosides | JANSSEN PHARACEUTICA, N.V. (BE) | 2006-08-22 | — | — | US | disclosed |
| US-20050037980-A1 | Substituted fused heterocyclic C-glycosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004160-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | UGCG, UGGT1, GCG | GPR84 2865/4885SLC5A2 7/4885SLC5A1 13/4885 |
| US-20060229260-A1 | Substituted fused heterocyclic C-glycosides | UGCG, UGGT1, GCG | GPR84 2865/4885SLC5A2 7/4885SLC5A1 13/4885 |
| US-20090105162-A1 | SUBSTITUTED FUSED HETEROCYCLIC C-GLYCOSIDES | UGCG, UGGT1, GCG | GPR84 2865/4885SLC5A2 7/4885SLC5A1 13/4885 |
| US-20050037980-A1 | Substituted fused heterocyclic C-glycosides | UGCG, UGGT1, GCG | GPR84 2865/4885SLC5A2 7/4885SLC5A1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.