Orthotolidine

Orthotolidine

SCHEMBL3410367

Cc1cc(-c2ccc(N)c(C)c2)ccc1N.N=C=O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.74
TDP1 Q9NUW8 8/20 0.74
ALDH1A1 P00352 8/20 0.74
TSHR P16473 6/20 0.74
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 4/20 0.39
S100B P04271 1/20 0.38
APP P05067 1/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 4/20 0.38
TP53 P04637 3/20 0.38
GFER P55789 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthotolidine SCHEMBL635398 1.00 CYP3A4 (0.74) CYP3A4TDP1ALDH1A1TSHRKMT2A
SCHEMBL28690517 0.92 TDP1 (0.63) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL28342351 0.91 TDP1 (0.61) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL1069890 0.89 TDP1 (0.59) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL29386552 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL29365329 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL49414 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20572998 0.84 CYP3A4 (0.85) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20572942 0.84 CYP3A4 (0.85) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20547383 0.84 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52052995-A None JP disclosed
EP-2586611-B1 COMPOSITE POROUS MEMBRANE, METHOD FOR PRODUCING COMPOSITE POROUS MEMBRANE AND BATTERY SEPARATOR USING SAME TORAY INDUSTRIES (JP) 2018-10-03 EP disclosed
US-9614212-B2 Method of producing composite porous membrane TORAY BATTERY SEPARATOR FILM CO., LTD. (JP) 2017-04-04 US disclosed
US-20150122400-A1 METHOD OF PRODUCING COMPOSITE POROUS MEMBRANE TORAY INDUSTRIES, INC. (JP) 2015-05-07 US disclosed
EP-2586611-A1 COMPOSITE POROUS MEMBRANE, METHOD FOR PRODUCING COMPOSITE POROUS MEMBRANE AND BATTERY SEPARATOR USING SAME Toray Industries, Inc. (JP) 2013-05-01 EP disclosed
US-20130101889-A1 COMPOSITE POROUS MEMBRANE, METHOD FOR PRODUCING COMPOSITE POROUS MEMBRANE AND BATTERY SEPARATOR USING SAME TORAY INDUSTRIES, INC. (JP) 2013-04-25 US disclosed
CN-101431892-B Liquid composition and preparation method thereof, exterior parasite remover for mammal and birds NIPPON SODA CO 2013-03-27 CN disclosed
US-8222365-B2 Polyamideimide resin, as well as a colorless and transparent flexible metal-clad laminate and circuit board obtained therefrom TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-17 US disclosed
US-20100018756-A1 POLYAMIDEIMIDE RESIN, AS WELL AS A COLORLESS AND TRANSPARENT FLEXIBLE METAL-CLAD LAMINATE AND CIRCUIT BOARD OBTAINED THEREFROM TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed
CN-100578047-C Sealing system NOK CORP 2010-01-06 CN disclosed
EP-2103641-A1 POLYAMIDE-IMIDE RESIN, COLORLESS TRANSPARENT FLEXIBLE METAL LAMINATE MADE OF THE SAME, AND WIRING BOARD Toyo Boseki Kabushiki Kaisha (JP) 2009-09-23 EP disclosed
CN-101431892-A Liquid composition and its preparation method, exterior parasite remover for mammal and birds NIPPON SODA CO (JP) 2009-05-13 CN disclosed
CN-1965185-A Sealing system NOK CORP (JP) 2007-05-16 CN disclosed
JP-2001011039-A PELLETAL o-TOLIDINE DIISOCYANATE NIPPON SODA CO LTD 2001-01-16 JP disclosed
JP-S5252995-A PREPARATION OF THERMOPLASTIC POLYURETHANE NIPPON SODA CO LTD 1977-04-28 JP disclosed