Orthotolidine

Orthotolidine

SCHEMBL635398

Cc1cc(-c2ccc(N)c(C)c2)ccc1N.N=C=O.N=C=O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.74
TDP1 Q9NUW8 8/20 0.74
ALDH1A1 P00352 8/20 0.74
TSHR P16473 6/20 0.74
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 4/20 0.39
S100B P04271 1/20 0.38
APP P05067 1/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 4/20 0.38
TP53 P04637 3/20 0.38
GFER P55789 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthotolidine SCHEMBL3410367 1.00 CYP3A4 (0.74) CYP3A4TDP1ALDH1A1TSHRKMT2A
SCHEMBL28690517 0.92 TDP1 (0.63) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL28342351 0.91 TDP1 (0.61) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL1069890 0.89 TDP1 (0.59) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL29386552 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL29365329 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL49414 0.86 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20572998 0.84 CYP3A4 (0.85) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20572942 0.84 CYP3A4 (0.85) CYP3A4TDP1ALDH1A1TSHRKMT2A
Orthotolidine SCHEMBL20547383 0.84 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916879-B Method for synthesizing an auxetic polyurethane foam having a defined cell structure and auxetic polyurethane foam obtainable by the method 思玛特材料有限公司 2024-04-30 CN claimed
EP-4337824-A1 ROLLER COVER AND ROLLER Voith Patent GmbH (DE) 2024-03-20 EP claimed
US-11859042-B2 Method for preparing a thermoplastic polyurethane having a low glass transition temperature BASF SE (DE) 2024-01-02 US claimed
CN-116640361-B Release agent composition and application thereof 益丰新材料股份有限公司 2023-12-22 CN claimed
CN-117126594-A Optical coating composition, optical coating and photovoltaic module comprising optical coating composition 浙江福斯特新材料研究院有限公司 2023-11-28 CN claimed
US-20230374190-A1 PRESS COVER FOR A SHOE PRESS OR TRANSPORT BELT WITH IMPROVED HYDROPHOBICITY VOITH PATENT GMBH (DE) 2023-11-23 US claimed
CN-116693790-A Composition for optical material and optical material 益丰新材料股份有限公司 2023-09-05 CN claimed
CN-116640361-A Release agent composition and application thereof 益丰新材料股份有限公司 2023-08-25 CN claimed
EP-4225990-A1 ROLLER COVER OR ROLLER WITH IMPROVED HYDROPHOBICITY Voith Patent GmbH (DE) 2023-08-16 EP claimed
EP-4225991-A1 PRESS SHELL FOR A SHOE PRESS OR TRANSPORT BELT WITH IMPROVED HYDROPHOBICITY Voith Patent GmbH (DE) 2023-08-16 EP claimed
US-20110300450-A1 POLYURETHANE GEL ELECTROLYTES WITH IMPROVED CONDUCTANCE AND/OR SOLVENT RETENTION INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) 2011-12-08 US claimed
EP-2203492-A1 SOFT, ELASTIC, PLASTICIZER-FREE THERMOPLASTIC POLYURETHANE AND PROCESS TO SYNTHESIZE THE SAME Lubrizol Advanced Materials, Inc. (US) 2010-07-07 EP claimed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US claimed
WO-2009055361-A1 SOFT, ELASTIC, PLASTICIZER-FREE THERMOPLASTIC POLYURETHANE AND PROCESS TO SYNTHESIZE THE SAME LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-04-30 WO claimed
US-20090100723-A1 Soft, Elastic, Plasticizer-Free Thermoplastic Polyurethane And Process To Synthesize The Same LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-04-23 US claimed
US-20080280142-A1 Preparation of organic additive-treated, pyrogenic silica-encapsulated titanium dioxide particles THE CHEMOURS COMPANY FC, LLC 2008-11-13 US claimed
EP-1900780-A1 Preparation of organic additive-treated, pyrogenic silica-encapsulated titanium dioxide particles E.I.Du pont de nemours and company (US) 2008-03-19 EP claimed
EP-1591490-A2 Preparation of organic additive-treated, pyrogenic silica-encapsulated titanium dioxide particles E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-11-02 EP claimed
US-20050239921-A1 Preparation of organic additive-treated, pyrogenic silica-encapsulated titanium dioxide particles E. I. DU PONT DE NEMOURS AND COMPANY 2005-10-27 US claimed
US-20050069692-A1 Method for coating porous polyurethane resin FOREX ASSET MANAGEMENT, INC. 2005-03-31 US claimed