SCHEMBL341111

SCHEMBL341111

C=C(C)C(=O)OC[Si](CC)(OC)OC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338995 0.87 THRB (0.47) THRBTSHRALDH1A1
SCHEMBL16537776 0.85 TSHR (0.44) THRBTSHRALDH1A1
SCHEMBL15258289 0.85 TSHR (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28546813 0.83 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL339142 0.81 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9111166 0.81 THRB (0.42) THRBTSHRALDH1A1
SCHEMBL339886 0.81 THRB (0.44) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16536937 0.79 TSHR (0.46) THRBTSHRALDH1A1
SCHEMBL340893 0.79 TSHR (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1803419 0.78 TSHR (0.44) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9645416-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2017-05-09 US claimed
CN-108467608-A Effect pigment 默克专利股份有限公司 2018-08-31 CN disclosed
US-9645416-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150129818-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2015-05-14 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed
WO-2013170937-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-11-21 WO disclosed
CN-101451050-B Pressure sensitive adhesive tape NITTO DENKO CORP 2013-07-10 CN disclosed
CN-103183972-A Effect pigments MERCK PATENT GMBH 2013-07-03 CN disclosed
CN-101675118-B Effect pigments comprising a glass flake substrate ECKART GMBH 2013-01-09 CN disclosed
EP-2065455-B1 Pressure-sensitive adhesive tape NITTO DENKO CORP (JP) 2012-05-16 EP disclosed
US-20120015100-A1 Pressure-Sensitive Adhesive Tape NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
EP-2383321-A2 Process for producing an adhesive composition and adhesive tape comprising an adhesive composition produced by said process Nitto Denko Corporation (JP) 2011-11-02 EP disclosed
CN-101675118-A Effect pigments comprising a glass flake substrate ECKART GMBH 2010-03-17 CN disclosed
CN-101451050-A Pressure sensitive adhesive tape NITTO DENKO CORP (JP) 2009-06-10 CN disclosed
US-20090142593-A1 PRESSURE-SENSITIVE ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2009-06-04 US disclosed
EP-2065455-A1 Pressure-sensitive adhesive tape NITTO DENKO CORPORATION (JP) 2009-06-03 EP disclosed
US-7186767-B2 Poly(ester) carbonate molding compositions BAYER AKTIENGESELLSCHAFT (DE) 2007-03-06 US disclosed
US-20040106731-A1 Poly(ester) carbonate molding compositions COVESTRO DEUTSCHLAND AG (DE) 2004-06-03 US disclosed