Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL341116

CCCCCCCCCCCCCCCCCC(=O)C(C)(Cl)C(=O)CCCCCCCCCCCCCCCCC.N.N

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.57
CES1 P23141 8/20 0.57
CES2 O00748 5/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
HSD17B10 Q99714 2/20 0.57
CYP1A2 P05177 1/20 0.57
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.52
PPARG P37231 4/20 0.48
PPARD Q03181 4/20 0.48
PPARA Q07869 4/20 0.48
GPR84 Q9NQS5 3/20 0.48
HDAC11 Q96DB2 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
TLR2 O60603 1/20 0.48
ESR1 P03372 1/20 0.48
FABP4 P15090 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26124164 0.98 FAAH (0.59) FAAHCES1CES2MEN1KMT2A
Dimethylamine SCHEMBL12980876 0.92 FAAH (0.53) FAAHCES1CES2MEN1KMT2A
Dimethylamine SCHEMBL5538214 0.92 FAAH (0.53) FAAHCES1CES2MEN1KMT2A
SCHEMBL7028971 0.84 FAAH (0.59) FAAHCES1CES2MEN1KMT2A
SCHEMBL28055566 0.82 FAAH (0.61) FAAHCES1CES2MEN1KMT2A
SCHEMBL9568273 0.82 FAAH (0.61) FAAHCES1CES2MEN1KMT2A
SCHEMBL7614009 0.82 FAAH (0.61) FAAHCES1CES2MEN1KMT2A
Ammonia Solution, Strong SCHEMBL4372487 0.82 FAAH (0.61) FAAHCES1CES2MEN1KMT2A
SCHEMBL27557547 0.80 FAAH (0.59) FAAHCES1CES2MEN1KMT2A
SCHEMBL23052919 0.79 FAAH (0.64) FAAHCES1CES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3459520-A1 HAIR DYEING COMPOSITION BASF SE (DE) 2019-03-27 EP disclosed
US-8268014-B2 Hair dyeing composition BASF SE Ludwigshafen (DE) 2012-09-18 US disclosed
US-8257448-B2 Hair dyeing composition BASF SE (DE) 2012-09-04 US disclosed
US-20120017931-A1 HAIR DYEING COMPOSITION BASF SE (DE) 2012-01-26 US disclosed
US-20120012128-A1 HAIR DYEING COMPOSITION BASF SE (DE) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012128-A1 HAIR DYEING COMPOSITION CYC1, CYB5R3, TYR FAAH 2534/4885CES1 1648/4885CES2 886/4885
US-20120017931-A1 HAIR DYEING COMPOSITION CYB5R3, CYC1, CYCS FAAH 2341/4885CES1 2032/4885CES2 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.