SCHEMBL341141

SCHEMBL341141

N=c1ccc2cccc(Nc3ccccc3)c2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.49
HSD17B10 Q99714 4/20 0.49
HPGD P15428 4/20 0.49
CYP3A4 P08684 3/20 0.49
ALOX15 P16050 2/20 0.49
TSHR P16473 2/20 0.49
CDC25B P30305 2/20 0.49
TP53 P04637 1/20 0.49
ATM Q13315 1/20 0.49
MAPT P10636 7/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
KDM4E B2RXH2 5/20 0.44
TDP1 Q9NUW8 5/20 0.44
GAA P10253 2/20 0.44
GLA P06280 2/20 0.44
RECQL P46063 2/20 0.44
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11577556 0.68 GLA (0.54) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL8415803 0.67 MAPT (0.59) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL30346387 0.67 MAPT (0.59) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL9718859 0.67 PIM1 (0.50) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL29350230 0.66 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL19796 0.66 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL444976 0.66 MAPT (0.70) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL9081346 0.66 MEN1 (0.46) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Ammonia Solution, Strong SCHEMBL20918916 0.65 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Diphenylamine SCHEMBL1072941 0.65 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016092-A1 Catalysts based on quinoline precursors BASELL POLYOLEFINE GMBH (DE) 2012-01-19 US claimed
WO-2012009369-A1 CATALYSTS BASED ON QUINOLINE PRECURSORS BASELL POLYOLEFINE GMBG (DE) 2012-01-19 WO claimed
CN-109563110-B Quinolinyldiamido transition metal complexes, their production and use 埃克森美孚化学专利公司 2021-08-20 CN disclosed
EP-3478694-B9 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-08-04 EP disclosed
EP-3478694-B1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-09 EP disclosed
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-27 US disclosed
US-10562987-B2 Polymers produced via use of quinolinyldiamido transition metal complexes and vinyl transfer agents EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-02-18 US disclosed
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2019-06-13 US disclosed
EP-3478694-A1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2019-05-08 EP disclosed
US-10208140-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-02-19 US disclosed
WO-2018160276-A1 POLYMERS PRODUCED VIA USE OF QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES AND VINYL TRANSFER AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-09-07 WO disclosed
US-20180134816-A1 Polymers Produced via Use of Quinolinyldiamido Transition Metal Complexes and Vinyl Transfer Agents EXXONMOBIL CHEMICAL PATENTS INC. 2018-05-17 US disclosed
US-20180002352-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2018-01-04 US disclosed
WO-2018005201-A1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-01-04 WO disclosed
US-20130023634-A1 CATALYST SYSTEM BASED ON QUINOLINE DONORS EQUISTAR CHEMICALS, LP 2013-01-24 US disclosed
US-20120016092-A1 Catalysts based on quinoline precursors BASELL POLYOLEFINE GMBH (DE) 2012-01-19 US disclosed
US-20120016092-A1 Catalysts based on quinoline precursors BASELL POLYOLEFINE GMBH (DE) 2012-01-19 US disclosed
WO-2012009369-A1 CATALYSTS BASED ON QUINOLINE PRECURSORS BASELL POLYOLEFINE GMBG (DE) 2012-01-19 WO disclosed
WO-2012009369-A1 CATALYSTS BASED ON QUINOLINE PRECURSORS BASELL POLYOLEFINE GMBG (DE) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208140-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM ALDH1A1 3944/4885HSD17B10 4268/4885HPGD 1151/4885
US-20180002352-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof PARN, PARG, PICALM ALDH1A1 3944/4885HSD17B10 4268/4885HPGD 1151/4885
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM ALDH1A1 3944/4885HSD17B10 4268/4885HPGD 1151/4885
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof PARN, PARG, PICALM ALDH1A1 3944/4885HSD17B10 4268/4885HPGD 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.