Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 10/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 10/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810983 | 0.85 | HMGB1 (0.40) | TSHRALDH1A1KDM4EP2RX1MAPT | |
| SCHEMBL580270 | 0.84 | KDM4E (0.47) | TSHRALDH1A1HTTKDM4ELMNA | |
| SCHEMBL580229 | 0.80 | PPARA (0.55) | ALDH1A1KDM4EMAPTPPARASTING1 | |
| SCHEMBL3996092 | 0.79 | PPARA (0.54) | ALDH1A1KDM4EMAPTPPARASTING1 | |
| Potassium SCHEMBL29515374 | 0.79 | PPARA (0.54) | ALDH1A1KDM4EMAPTPPARASTING1 | |
| SCHEMBL3996747 | 0.79 | PPARA (0.54) | ALDH1A1KDM4EMAPTPPARASTING1 | |
| SCHEMBL3996778 | 0.79 | PPARA (0.54) | ALDH1A1KDM4EMAPTPPARASTING1 | |
| SCHEMBL27545640 | 0.78 | GAA (0.42) | TSHRALDH1A1HTTKDM4ELMNA | |
| SCHEMBL581497 | 0.77 | PPARA (0.40) | TSHRALDH1A1HTTKDM4ELMNA | |
| SCHEMBL581259 | 0.77 | KDM4C (0.42) | TSHRALDH1A1HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216749-A1 | Combination Therapy for Neuroprotection | S.H. PHARMA., LTD (KR) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216749-A1 | Combination Therapy for Neuroprotection | MPO, BDNF, NLN | AKR1C2 2738/4885AKR1C1 2609/4885AKR1C4 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.