SCHEMBL3412619

SCHEMBL3412619

C=CCNC(=O)C(C)(C)N=NC(C)(C)C(=O)C=C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 2/20 0.34
FAAH O00519 1/20 0.34
PKM P14618 1/20 0.31
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157278 0.91 SMN1; SMN2 (0.42) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL157277 0.91 SMN1; SMN2 (0.42) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL6888023 0.81 CNR1 (0.38) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL6888021 0.81 CNR1 (0.38) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL18639178 0.80 TSHR (0.34) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL15355958 0.78 SMN1; SMN2 (0.41) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL10067689 0.77 SMN1; SMN2 (0.39) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL10818200 0.73 TSHR (0.46) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL13875007 0.73 ALDH1A1 (0.35) MAPTALDH1A1KMT2ALMNA
SCHEMBL1520813 0.71 FAAH (0.40) TSHRSMN1; SMN2MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067939-A1 NUCLEIC ACID AMPLIFICATION Life Technologies Corporation 2024-02-29 US disclosed
US-11725195-B2 Nucleic acid amplification Life Technologies Corporation (US) 2023-08-15 US disclosed
US-20230175046-A1 MATRIX ARRAYS AND METHODS FOR MAKING SAM LIFE TECHNOLOGIES CORP (US) 2023-06-08 US disclosed
US-20180179520-A1 SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING LIFE TECHNOLOGIES CORP (US) 2018-06-28 US disclosed
US-20170263922-A1 ACTIVE MATERIAL-EXFOLIATED GRAPHITE COMPOSITE, NEGATIVE ELECTRODE MATERIAL FOR LITHIUM ION SECONDARY BATTERY, AND LITHIUM ION SECONDARY BATTERY SEKISUI CHEMICAL CO., LTD. (JP) 2017-09-14 US disclosed
US-9711786-B2 Fine particle-exfoliated graphite composite, negative electrode material for lithium ion secondary battery, and methods for producing the same, and lithium ion secondary battery SEKISUI CHEMICAL CO., LTD. (JP) 2017-07-18 US disclosed
US-20160358718-A1 CAPACITOR ELECTRODE MATERIAL, METHOD FOR PRODUCING SAME, AND ELECTRIC DOUBLE LAYER CAPACITOR SEKISUI CHEMICAL CO., LTD. (JP) 2016-12-08 US disclosed
US-20160272954-A1 NUCLEIC ACID AMPLIFICATION Life Technologies Corporation 2016-09-22 US disclosed
US-9371557-B2 Nucleic acid amplification Life Technologies Corporation (US) 2016-06-21 US disclosed
US-9309557-B2 Nucleic acid amplification Life Technologies Corporation (US) 2016-04-12 US disclosed
US-9309558-B2 Nucleic acid amplification Life Technologies Corporation (US) 2016-04-12 US disclosed
US-20160032375-A1 NUCLEIC ACID AMPLIFICATION Life Technologies Corporation 2016-02-04 US disclosed
US-20150270534-A1 FINE PARTICLE-EXFOLIATED GRAPHITE COMPOSITE, NEGATIVE ELECTRODE MATERIAL FOR LITHIUM ION SECONDARY BATTERY, AND METHODS FOR PRODUCING THE SAME, AND LITHIUM ION SECONDARY BATTERY SEKISUI CHEMICAL CO., LTD. (JP) 2015-09-24 US disclosed
US-20130281307-A1 NUCLEIC ACID AMPLIFICATION Life Technologies Corporation 2013-10-24 US disclosed
US-20130225421-A1 NUCLEIC ACID AMPLIFICATION Life Technologies Corporation (US) 2013-08-29 US disclosed
US-20120094871-A1 Particle Population and Methods of Making and Using Life Technologies Corporation (US) 2012-04-19 US disclosed
US-20110201523-A1 Particle Arrays and Methods of Making and Using Life Technologies Corporation (US) 2011-08-18 US disclosed
US-20110195459-A1 Methods of Making Libraries of Nucleic Acids Using Porous Particles Life Technologies Corporation (US) 2011-08-11 US disclosed
US-20110195253-A1 Scaffolded Nucleic Acid Polymer Particles and Methods of Making and Using Life Technologies Corporation (US) 2011-08-11 US disclosed