SCHEMBL157278

SCHEMBL157278

C=CCNC(=O)C(C)(C)N=NC(C)(C)C(=O)NCC=C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 2/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 5/20 0.40
KMT2A Q03164 2/20 0.39
FAAH O00519 1/20 0.39
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.34
HPGD P15428 4/20 0.34
MEN1 O00255 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157277 1.00 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL3412619 0.91 TSHR (0.36) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL6888023 0.89 CNR1 (0.38) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL6888021 0.89 CNR1 (0.38) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL18639178 0.88 TSHR (0.34) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL15355958 0.86 SMN1; SMN2 (0.41) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL10067689 0.84 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL10818200 0.80 TSHR (0.46) SMN1; SMN2TSHRMAPTALDH1A1KMT2A
SCHEMBL13875007 0.80 ALDH1A1 (0.35) MAPTALDH1A1KMT2ALMNA
SCHEMBL1520813 0.79 FAAH (0.40) SMN1; SMN2TSHRMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119857451-A Methyl methacrylate polymer preparation device and preparation method thereof 岚迪智慧科技(南通)有限公司 2025-04-22 CN claimed
CN-113999339-B Method for preparing polymethyl methacrylate 金聚合科技(宁波)有限公司 2023-04-07 CN claimed
US-11427659-B2 Method of preparing acrylonitrile-based polymer for producing carbon fiber LG CHEM, LTD. (KR) 2022-08-30 US claimed
US-11390696-B2 Control over controlled radical polymerization processes PILOT POLYMER TECHNOLOGIES, INC. (US) 2022-07-19 US claimed
EP-3752562-B1 FLUOROELASTOMER CURABLE COMPOSITION SOLVAY SPECIALTY POLYMERS IT (IT) 2022-01-12 EP claimed
EP-3873985-A1 CURABLE COMPOSITION OF ELASTOMERS Solvay Specialty Polymers Italy S.p.A. (IT) 2021-09-08 EP claimed
WO-2021123114-A1 BASE-RESISTANT FLUOROELASTOMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-06-24 WO claimed
US-11034882-B2 Method for inhibiting water permeation in an extraction well of a hydrocarbon oil from an underground reservoir ENI S.P.A. (IT) 2021-06-15 US claimed
WO-2021099336-A1 METHOD FOR IMPROVING COEFFICIENT OF FRICTION IN CURED FLUORORUBBER PARTS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-05-27 WO claimed
EP-3794047-A1 HEAT-SHRINKABLE ARTICLE Solvay Specialty Polymers Italy S.p.A. (IT) 2021-03-24 EP claimed
EP-2165828-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2011-11-09 EP claimed
US-20100174040-A1 PROCESS FOR PREPARING ACRYLATE COPOLYMERS BASF SE (DE) 2010-07-08 US claimed
US-20100160574-A1 Polymerisation Using Chain Transfer Agents THE UNIVERSITY OF LEEDS (GB) 2010-06-24 US claimed
US-20090215965-A1 POLYMERISATION USING CHAIN TRANSFER AGENTS THE UNIVERSITY OF LEEDS (GB) 2009-08-27 US claimed
EP-2004700-A1 PROCESS FOR PREPARING ACRYLATE COPOLYMERS BASF SE (DE) 2008-12-24 EP claimed
US-20070299221-A1 Polymerisation Using Chain Transfer Agents UNIVERSITY OF LEEDS, THE (GB) 2007-12-27 US claimed
WO-2007113129-A1 PROCESS FOR PREPARING ACRYLATE COPOLYMERS BASF SE (DE) 2007-10-11 WO claimed
EP-1697424-A1 POLYMERISATION USING CHAIN TRANSFER AGENTS THE UNIVERSITY OF LEEDS (GB) 2006-09-06 EP claimed
US-20060003109-A1 PROCESS FOR CURING PAINT DAIMLER AG (DE) 2006-01-05 US claimed
WO-2005061555-A1 POLYMERISATION USING CHAIN TRANSFER AGENTS THE UNIVERSITY OF LEEDS (GB) 2005-07-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160574-A1 Polymerisation Using Chain Transfer Agents TRRAP, TRMT1, IPO11 SMN1; SMN2 4353/4885TSHR 1796/4885MAPT 3288/4885
US-20090215965-A1 POLYMERISATION USING CHAIN TRANSFER AGENTS TRRAP, TRMT1, IPO11 SMN1; SMN2 4353/4885TSHR 1796/4885MAPT 3288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.