Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413099 | 0.76 | HSD11B1 (0.43) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL7701143 | 0.75 | ALDH1A1 (0.50) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL2955033 | 0.72 | S1PR1 (0.56) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL277877 | 0.70 | S1PR1 (0.48) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL455625 | 0.70 | SCN9A (0.44) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL20570250 | 0.68 | ALDH1A1 (0.40) | HSD11B1SCN9AL3MBTL1ALDH1A1KCNN4 | |
| SCHEMBL19199851 | 0.68 | RORC (0.47) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL27610710 | 0.68 | SCN9A (0.48) | SCN9AL3MBTL1GPR3TRPA1KDM4E | |
| SCHEMBL1045874 | 0.67 | FFAR4 (0.51) | HSD11B1SCN9AS1PR1L3MBTL1ALDH1A1 | |
| SCHEMBL5545746 | 0.67 | SCN9A (0.60) | SCN9AL3MBTL1TRPA1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260032-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |