Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658997 | 0.83 | HDAC1 (0.43) | HDAC1POLBGAAALDH1A1KDM4E | |
| SCHEMBL27736941 | 0.75 | KDM4E (0.59) | HDAC1POLBGAAALDH1A1KDM4E | |
| SCHEMBL1656642 | 0.73 | HDAC3 (0.55) | HDAC1POLBALDH1A1HDAC3TSHR | |
| SCHEMBL1656633 | 0.70 | L3MBTL1 (0.60) | HDAC1ALDH1A1HDAC3TSHRHDAC2 | |
| SCHEMBL1655297 | 0.70 | MAPT (0.42) | HDAC1ALDH1A1HDAC3HDAC2HDAC4 | |
| SCHEMBL1659367 | 0.69 | POLB (0.54) | HDAC1POLBGAAALDH1A1KDM4E | |
| SCHEMBL6226752 | 0.68 | GABRP (0.57) | HDAC1POLBALDH1A1KDM4E | |
| SCHEMBL1938823 | 0.67 | HDAC3 (0.77) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL38661880 | 0.67 | HDAC1 (0.47) | HDAC1POLBGAAALDH1A1KDM4E | |
| SCHEMBL5103850 | 0.67 | MEN1 (0.54) | HDAC1POLBGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-A2 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111576-A2 | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |