Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007213 | 0.87 | FBP1 (0.47) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL2007670 | 0.79 | LMNA (0.56) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL3410883 | 0.76 | HTT (0.54) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL2008042 | 0.73 | FBP1 (0.53) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL2007912 | 0.73 | FBP1 (0.53) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL2012755 | 0.71 | KMT2A (0.56) | FBP1TSHRALDH1A1HTTMEN1 | |
| SCHEMBL2008078 | 0.71 | SMN1; SMN2 (0.55) | FBP1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2015204 | 0.70 | FBP1 (0.47) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL2008704 | 0.68 | FBP1 (0.48) | FBP1CYP2C9TSHRALDH1A1LMNA | |
| SCHEMBL26144891 | 0.67 | NPSR1 (0.47) | CYP2C9ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081889-B1 | SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-12-22 | — | — | EP | claimed |