Biphenyl

Biphenyl

SCHEMBL341377

C[C@H](N)C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.60
PTGS2 P35354 1/20 0.59
PKM P14618 2/20 0.53
CYP1A2 P05177 1/20 0.53
GAA P10253 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
PDCD1 Q15116 1/20 0.48
CD274 Q9NZQ7 1/20 0.48
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ADAMTS4 O75173 1/20 0.47
SLC1A5 Q15758 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
ALDH1A1 P00352 1/20 0.45
ALPI P09923 1/20 0.45
PTGS1 P23219 1/20 0.45
XIAP P98170 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL157604 1.00 TAAR1 (0.60) TAAR1PTGS2PKMCYP1A2GAA
Tannin Pyrogallol SCHEMBL27714315 0.98 TAAR1 (0.63) TAAR1PTGS2PKMCYP1A2GAA
Tannin Pyrogallol SCHEMBL27714316 0.98 TAAR1 (0.63) TAAR1PTGS2PKMCYP1A2GAA
Alanine SCHEMBL4258116 0.90 TAAR1 (0.53) TAAR1PTGS2PKMCYP1A2GAA
Alanine SCHEMBL28776159 0.89 KMT2A (0.50) TAAR1PTGS2PKMCYP1A2GAA
Alanine SCHEMBL4261908 0.86 TAAR1 (0.47) TAAR1PTGS2
Naphthalene SCHEMBL699808 0.85 TAAR1 (0.46) TAAR1PTGS2PKMCYP1A2ALDH1A1
Naphthalene SCHEMBL699807 0.85 TAAR1 (0.46) TAAR1PTGS2PKMCYP1A2ALDH1A1
Alanine SCHEMBL3667125 0.84 CYP1A2 (0.59) TAAR1PTGS2PKMCYP1A2GAA
Alanine SCHEMBL3667123 0.84 CYP1A2 (0.59) TAAR1PTGS2PKMCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026162-A Cystine knot scaffold platform 豪夫迈·罗氏有限公司 2018-05-11 CN claimed
CN-106399412-A Method for synthesizing D-biphenyl alanine 南京红杉生物科技有限公司 2017-02-15 CN claimed
CN-103429269-B Contain with the coupling of polyanion polypeptide, derived from the conjugated molecule that is used for the treatment of AIDS of the peptide of CD4 acceptor INSTITUT PASTEUR (FR) 2016-05-11 CN claimed
CN-105143245-A Anti-scaling material YISSUM RES DEV CO 2015-12-09 CN claimed
CN-103429269-A New conjugated molecules comprising peptide derived from CD4 receptor coupled to polyanionic polypeptide for treatment of AIDS PASTEUR INSTITUT 2013-12-04 CN claimed
CN-101370943-B Process for producing optically active biphenylalanine compound or salt or ester thereof SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-15 CN claimed
CN-102015758-A Oligopeptidic compounds and uses thereof APIM THERAPEUTICS AS 2011-04-13 CN claimed
CN-101516909-A CD4-receptor-derived peptides and method for the preparation thereof PASTEUR INSTITUT (FR) 2009-08-26 CN claimed
CN-101466391-A Inhibition of tumor growth LYTIX BIOPHARMA AS (NO) 2009-06-24 CN claimed
CN-101370943-A Process for producing optically active biphenylalanine compound or salt or ester thereof SUMITOMO CHEMICAL CO (JP) 2009-02-18 CN claimed
CN-101262874-A Stabilized GLP-1 analogs TUFTS COLLEGE (US) 2008-09-10 CN claimed
CN-101048506-A Orthogonal translation Components for in vivo incorporation of unnatural amino acids SCRIPPS RESEARCH INST (US) 2007-10-03 CN claimed
CN-1662551-A Antagonistic peptides of prostaglandin e2 receptor subtype ep4 THERATECHNOLOGIES INC (CA) 2005-08-31 CN claimed
EP-0910579-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1999-04-28 EP claimed
WO-1997040071-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-10-30 WO claimed
US-12404512-B2 Method for optimizing antibody expression AMBRX, INC. (US) 2025-09-02 US disclosed
WO-2024119277-A1 KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-06-13 WO disclosed
WO-1999026923-A1 PARA-AMINOMETHYLARYL CARBOXAMIDE DERIVATIVES MERCK & CO., INC. (US) 1999-06-03 WO disclosed
EP-0910579-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1999-04-28 EP disclosed
WO-1997040071-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed