Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL341377 | 0.86 | TAAR1 (0.60) | TAAR1PTGS2 | |
| Biphenyl SCHEMBL157604 | 0.86 | TAAR1 (0.60) | TAAR1PTGS2 | |
| SCHEMBL3478959 | 0.86 | KMO (0.50) | KMORXRARXRBRXRGPTGS2 | |
| Lactic Acid SCHEMBL3962098 | 0.84 | TP53 (0.52) | KMORXRARXRBRXRGPTGS2 | |
| Tannin Pyrogallol SCHEMBL27714315 | 0.84 | TAAR1 (0.63) | TAAR1PTGS2 | |
| Tannin Pyrogallol SCHEMBL27714316 | 0.84 | TAAR1 (0.63) | TAAR1PTGS2 | |
| Threonine SCHEMBL1882390 | 0.84 | PTGS2 (0.43) | KMOGRIA2RXRARXRBRXRG | |
| SCHEMBL28789662 | 0.82 | KMO (0.47) | KMOGRIA2RXRARXRBDHODH | |
| SCHEMBL8927749 | 0.82 | KMO (0.47) | KMORXRARXRBRXRGPTGS2 | |
| Alanine SCHEMBL28922813 | 0.81 | ELANE (0.42) | TAAR1PTGS2LMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| CN-102369026-A | Pcl/pga hemostatic foams | ETHICON INC | 2012-03-07 | — | — | CN | disclosed |
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | disclosed |
| EP-1734991-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | Avirid, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005115444-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | AVIRID, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| WO-1999065435-A1 | HYDROGEL BODY | CENES DRUG DELIVERY LIMITED (GB) | 1999-12-23 | — | — | WO | disclosed |