Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tannin Pyrogallol SCHEMBL27714316 | 0.93 | TAAR1 (0.63) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| Tannin Pyrogallol SCHEMBL27714315 | 0.93 | TAAR1 (0.63) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| Benzidine SCHEMBL15658492 | 0.91 | MMP1 (0.51) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| Biphenyl SCHEMBL157604 | 0.90 | TAAR1 (0.60) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| Biphenyl SCHEMBL341377 | 0.90 | TAAR1 (0.60) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| SCHEMBL27658907 | 0.82 | PTGS2 (0.44) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| SCHEMBL27585462 | 0.82 | PTGS2 (0.56) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| SCHEMBL11835743 | 0.82 | PTGS2 (0.56) | TAAR1PTGS2CYP1A2GAACYP2C9 | |
| Alanine SCHEMBL21616532 | 0.82 | SLC7A5 (0.53) | TAAR1PKMSLC7A5MAPTSLC1A3 | |
| Alanine SCHEMBL27615995 | 0.82 | SLC7A5 (0.53) | TAAR1PKMSLC7A5MAPTSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104780944-B | Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other diseases | 不列颠哥伦比亚癌症局分支机构 | 2020-03-17 | — | — | CN | disclosed |
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20090047272-A1 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases | NANONASE, INC. | 2009-02-19 | — | — | US | disclosed |
| EP-1734991-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | Avirid, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005115444-A2 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | AVIRID, INC. (US) | 2005-12-08 | — | — | WO | disclosed |