Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL699808 | 1.00 | TAAR1 (0.46) | TAAR1ALPIPKMPTGS1XIAP | |
| Anthracene SCHEMBL29064584 | 0.89 | EPHX1 (0.44) | TAAR1ALPIPKMPTGS1XIAP | |
| Biphenyl SCHEMBL157604 | 0.85 | TAAR1 (0.60) | TAAR1ALPIPKMPTGS1XIAP | |
| Biphenyl SCHEMBL341377 | 0.85 | TAAR1 (0.60) | TAAR1ALPIPKMPTGS1XIAP | |
| Alanine SCHEMBL28161213 | 0.85 | CYP1A2 (0.40) | TAAR1ALPIPKMPTGS1XIAP | |
| Phenazine SCHEMBL28705329 | 0.84 | ALDH1A1 (0.50) | PTGS2KDM4EALDH1A1ELANECTRB1 | |
| Pyrene SCHEMBL4782088 | 0.84 | KMT2A (0.50) | TAAR1XIAPKDM4ELMNAHIF1A | |
| Alanine SCHEMBL21616532 | 0.84 | SLC7A5 (0.53) | TAAR1ALPIPKMPTGS1XIAP | |
| Alanine SCHEMBL27615995 | 0.84 | SLC7A5 (0.53) | TAAR1ALPIPKMPTGS1XIAP | |
| Phenol SCHEMBL2786796 | 0.83 | CA12 (0.52) | TAAR1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109328067-A | The CD47 agonist of inducement of apoptosis and its purposes for the treatment of procedure cell death defect related disease | 索邦大学 | 2019-02-12 | — | — | CN | claimed |
| CN-117866042-A | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-04-12 | — | — | CN | disclosed |
| CN-117580857-A | APOC-II short mimetic peptides and methods of use | 美国政府(由卫生和人类服务部的部长所代表) | 2024-02-20 | — | — | CN | disclosed |
| CN-110114075-B | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-01-12 | — | — | CN | disclosed |
| CN-111278846-B | Antimicrobial tetrapeptides | 帝斯曼知识产权资产管理有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-107105707-B | Proline tolerant tripeptidylpeptidases and uses thereof | 杜邦营养生物科学有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114437226-A | Methods of making bispecific antibodies | 杭州菁因康生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-107810008-B | PIRIN polypeptides and immunomodulation | 4D制药研究有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-107105709-B | Use of proline tolerant tripeptidyl peptidase in feed additive composition | 杜邦营养生物科学有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-110114075-A | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2019-08-09 | — | — | CN | disclosed |
| CN-106466475-A | Composite formed by combining antibacterial peptide and polymer, preparation method and application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-01 | — | — | CN | disclosed |
| EP-2423223-B1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | PEGBIO CO LTD (CN) | 2015-04-15 | — | — | EP | disclosed |
| US-8575097-B2 | Exendin variant and conjugate thereof | PEGBIO CO., LTD. (CN) | 2013-11-05 | — | — | US | disclosed |
| US-20120196795-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | PEGBIO CO., LTD. (CN) | 2012-08-02 | — | — | US | disclosed |
| EP-2423223-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | Pegbio Co., Ltd. (CN) | 2012-02-29 | — | — | EP | disclosed |
| CN-100425284-C | Methods for glucagon suppression | AMYLIN PHARMACEUTICALS INC (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-1819837-A | TAMANDARIN analogs and fragments thereof and methods of making and using | JOULLIE MADELEINE M (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1659276-A | Phospholipases, nucleic acids encoding them and methods of making and using them | DIVERSA CORP (US) | 2005-08-24 | — | — | CN | disclosed |
| CN-1549722-A | Anti-cancer and wound healing compounds | 金伯利-克拉克环球有限公司 | 2004-11-24 | — | — | CN | disclosed |
| CN-1347327-A | Methods for glucagon suppression | AMYLIN PHARMACEUTICALS INC (US) | 2002-05-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196795-A1 | NOVEL EXENDIN VARIANT AND CONJUGATE THEREOF | GLP1R, IAPP, GIPR | TAAR1 4541/4885ALPI 2755/4885PKM 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.