Sugi Predict

Sugi Predict / Compounds / SCHEMBL3414993

SCHEMBL3414993

SCHEMBL3414993

O[C@H]1CCCC[C@@H]1c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC18A3 Q16572 10/20 0.59
▸ MEN1 O00255 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ CYP2D6 P10635 2/20 0.50
▸ TSHR P16473 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ SIGMAR1 Q99720 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.49
▸ APEX1 P27695 1/20 0.49
▸ BLM P54132 1/20 0.49
▸ GAA P10253 1/20 0.45
▸ HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149307 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL15061117 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL3693152 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL3869911 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL5163055 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL14026071 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL8746667 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL407263 1.00 SLC18A3 (0.59) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL15464620 0.98 SLC18A3 (0.57) SLC18A3MEN1KMT2ACYP2D6TSHR
SCHEMBL15464618 0.98 SLC18A3 (0.57) SLC18A3MEN1KMT2ACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025087282-A1 METHOD FOR PREPARING CHIRAL ALCOHOL COMPOUND 中国科学院上海有机化学研究所 2025-05-01 — — WO claimed
CN-111138243-B Preparation method of (1S,2R) -2-phenylcyclohexanol 郑州手性药物研究院有限公司 2022-06-24 — — CN claimed
CN-111138243-A Preparation method of (1S,2R) -2-phenylcyclohexanol 郑州手性药物研究院有限公司 2020-05-12 — — CN claimed
US-8471067-B2 Stereoselective preparation of P-chiral four-co-ordinated phosphorus compound (o-Tolylphenylmethylphosphine oxide) by reacting chiral alcohol, chiral amine or chiral thiol, with P-chiral three-co-ordinated phosphorus compound, in presence of electrophile UNIVERSITY COLLEGE DUBLIN (IE) 2013-06-25 — — US claimed
US-7507843-B2 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2009-03-24 — — US claimed
US-20080255391-A1 Chiral Phosphorus Compounds UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND (IE) 2008-10-16 — — US claimed
JP-2008501010-A — — 2008-01-17 — — JP claimed
EP-1675839-B1 STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS BOEHRINGER INGELHEIM PHARMA (US) 2007-07-11 — — EP claimed
US-7214834-B2 Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives EASTMAN KODAK COMPANY (US) 2007-05-08 — — US claimed
EP-1751170-A1 CHIRAL PHOSPHORUS COMPOUNDS UNIVERSITY COLLEGE DUBLIN (IE) 2007-02-14 — — EP claimed
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives EASTMAN KODAK COMPANY 2006-01-26 — — US claimed
WO-2005118603-A1 CHIRAL PHOSPHORUS COMPOUNDS UNIVERSITY COLLEGE DUBLIN (IE) 2005-12-15 — — WO claimed
US-20050131241-A1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2005-06-16 — — US claimed
US-5663265-A FREE RADICAL COPOLYMERIZATION FOR COATINGS HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-02 — — US claimed
US-5596057-A INTERPOLYMER FROM STERICALLY HINDERED UNSATURATED ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-21 — — US claimed
US-5420366-A Hydrogenolysis HOECHST CELANESE CORPORATION (US) 1995-05-30 — — US claimed
US-5294737-A Hydrolysis, cyclization, condensation THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 1994-03-15 — — US claimed
US-5137887-A Xanthine oxidase inhibitors, antipodagric agents OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1992-08-11 — — US claimed
US-20260022095-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF ADAMA AGAN LTD. (IL) 2026-01-22 — — US disclosed
EP-0343474-A2 Process for the preparation of optically pure aminophenylthio- and aminoaphthalenylthio-propanoic acids F. HOFFMANN-LA ROCHE AG (CH) 1989-11-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives HSD11B1, PKD1, REN SLC18A3 4701/4885MEN1 1196/4885KMT2A 4254/4885
US-20260022095-A1 COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF TET1, FOXK1, TET3 SLC18A3 3783/4885MEN1 4270/4885KMT2A 340/4885
US-20050131241-A1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols CBR3, ADH1C, C5 SLC18A3 3421/4885MEN1 1656/4885KMT2A 1536/4885
US-20080255391-A1 Chiral Phosphorus Compounds PHOSPHO1, PNKP, PTMS SLC18A3 2601/4885MEN1 3668/4885KMT2A 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.