Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 7/20 | 0.58 |
| ▸ | ACHE | P22303 | 7/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | PLK1 | P53350 | 4/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.55 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577550 | 0.99 | NR1H4 (0.61) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6581893 | 0.94 | BCHE (0.55) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6577993 | 0.90 | PLK1 (0.61) | PLK1PLK3 | |
| SCHEMBL6581823 | 0.88 | PLK1 (0.58) | NR1H4PLK1PLK3SMN1; SMN2 | |
| SCHEMBL6577738 | 0.87 | NPC1 (0.63) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6577703 | 0.87 | PLK1 (0.64) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL7476882 | 0.86 | NR1H4 (0.58) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL3088276 | 0.85 | NR1H4 (0.61) | NR1H4PLK1CYSLTR2CYSLTR1ABCC4 | |
| SCHEMBL6580071 | 0.84 | PLK1 (0.58) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL28418450 | 0.84 | PLK1 (0.60) | NR1H4BCHEACHEBACE1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10087590-A | — | — | None | — | — | JP | disclosed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | disclosed |
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| EP-0670835-B1 | PROCESS FOR PREPARING BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| EP-0920427-B1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-11-20 | — | — | EP | disclosed |
| US-6048983-A | Process for the preparation of benzopyran compounds | SMITHKLINE BEECHAM PL.C (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0920427-A1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-06-09 | — | — | EP | disclosed |
| JP-H1087590-A | PRODUCTION OF CARBOXYLIC ACID AMIDE COMPOUND | SHOWA KAKO KK | 1998-04-07 | — | — | JP | disclosed |
| WO-1998006718-A1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1998-02-19 | — | — | WO | disclosed |
| US-5675036-A | Process for preparing aromatic amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| US-5616721-A | Process for preparing benzopyran compounds | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| US-5596103-A | Process for preparing benzopyran compounds | SMITHKLINE BEECHAM PLC (GB) | 1997-01-21 | — | — | US | disclosed |
| US-5587483-A | Process for preparing tetrazol-5-yl substituted benzopyran compounds | SMITHKLINE BEECHAM PLC (GB) | 1996-12-24 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |
| EP-0670835-A1 | PROCESS FOR PREPARING BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012492-A1 | PROCESS FOR PREPARING BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-09 | — | — | WO | disclosed |