Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.58 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415084 | 0.86 | NR1H4 (0.62) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6577550 | 0.85 | NR1H4 (0.61) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL9713250 | 0.83 | KCNMA1 (0.62) | NR1H4CYSLTR1CYSLTR2MEN1NPC1 | |
| SCHEMBL9713649 | 0.81 | NR1H4 (0.63) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6581838 | 0.80 | NR1H4 (0.68) | NR1H4BCHEACHEBACE1CYSLTR1 | |
| SCHEMBL6581893 | 0.79 | BCHE (0.55) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6580317 | 0.79 | NR1H4 (0.67) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL9713671 | 0.78 | NR1H4 (0.64) | NR1H4PLK1CYSLTR1CYSLTR2MEN1 | |
| SCHEMBL9857004 | 0.77 | NR1H4 (0.56) | NR1H4CYSLTR1CYSLTR2MEN1NPC1 | |
| SCHEMBL10719026 | 0.77 | NR1H4 (0.55) | NR1H4CYSLTR1CYSLTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920427-B1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-11-20 | — | — | EP | disclosed |
| US-6048983-A | Process for the preparation of benzopyran compounds | SMITHKLINE BEECHAM PL.C (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0920427-A1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006718-A1 | PROCESS FOR THE PREPARATION OF BENZOPYRAN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1998-02-19 | — | — | WO | disclosed |