Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 10/20 | 0.61 |
| ▸ | PLK3 | Q9H4B4 | 7/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581823 | 0.97 | PLK1 (0.58) | PLK1PLK3TRPV1SLC16A3HDAC1 | |
| SCHEMBL6579934 | 0.90 | PLK1 (0.61) | PLK1PLK3TRPV1ABCG2 | |
| SCHEMBL3415084 | 0.90 | NR1H4 (0.62) | PLK1PLK3 | |
| SCHEMBL6577550 | 0.89 | NR1H4 (0.61) | PLK1PLK3 | |
| SCHEMBL3381862 | 0.85 | POLB (0.56) | HDAC1HDAC3HDAC2 | |
| SCHEMBL6581893 | 0.85 | BCHE (0.55) | PLK1ABCG2 | |
| SCHEMBL6580254 | 0.84 | NR1H4 (0.53) | PLK1PLK3TRPV1SLC16A3HDAC1 | |
| SCHEMBL6580165 | 0.82 | KDM4E (0.53) | TRPV1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL6577738 | 0.82 | NPC1 (0.63) | PLK1HDAC1HDAC3HDAC2 | |
| SCHEMBL6580460 | 0.81 | NPC1 (0.48) | SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |