Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 7/20 | 0.60 |
| ▸ | ACHE | P22303 | 7/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | PLK1 | P53350 | 4/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415084 | 0.99 | NR1H4 (0.62) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6581893 | 0.93 | BCHE (0.55) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6577993 | 0.89 | PLK1 (0.61) | PLK1PLK3 | |
| SCHEMBL6581823 | 0.87 | PLK1 (0.58) | NR1H4PLK1PLK3SMN1; SMN2 | |
| SCHEMBL6577738 | 0.86 | NPC1 (0.63) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL6577703 | 0.86 | PLK1 (0.64) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL7476882 | 0.85 | NR1H4 (0.58) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL3088276 | 0.84 | NR1H4 (0.61) | NR1H4PLK1CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL6580071 | 0.83 | PLK1 (0.58) | NR1H4BCHEACHEBACE1PLK1 | |
| SCHEMBL28418450 | 0.83 | PLK1 (0.60) | NR1H4BCHEACHEBACE1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |