SCHEMBL3415262

SCHEMBL3415262

COc1ccc(Oc2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 1.00
ESR2 Q92731 2/20 0.74
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
ESR1 P03372 1/20 0.74
APP P05067 2/20 0.64
NR1H2 P55055 1/20 0.61
BAX Q07812 1/20 0.61
CALM1 P0DP23 1/20 0.59
GAA P10253 1/20 0.59
PKM P14618 1/20 0.59
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
PARP10 Q53GL7 1/20 0.54
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23074268 1.00 LTA4H (1.00) LTA4HESR2MEN1KMT2AESR1
SCHEMBL26766402 0.93 LTA4H (0.86) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL21009 0.92
Mequinol SCHEMBL166535 0.92 ESR2 (0.84) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL1535640 0.92 ESR2 (0.84) LTA4HESR2MEN1KMT2AESR1
1,4-Dimethoxybenzene SCHEMBL8351066 0.92 ESR2 (0.84) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL16338066 0.89 ESR2 (0.80) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL20696082 0.89 ESR2 (0.80) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL2424246 0.89 ESR2 (0.80) LTA4HESR2MEN1KMT2AESR1
Mequinol SCHEMBL28560858 0.89 ESR2 (0.80) LTA4HESR2MEN1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023090964-A1 SILVER PLATING SOLUTION (주)피이솔브 2023-05-25 WO disclosed
CN-108026364-B Flame retardant polycarbonate compositions, methods of making and using the same 沙特基础工业全球技术有限公司 2020-02-21 CN disclosed
US-20150344662-A1 POLYETHERIMIDE POROUS BODY AND METHOD FOR PRODUCING SAME NITTO DENKO CORPORATION (JP) 2015-12-03 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-7767739-B2 Cyanato group-containing cyclic phosphazene compound and method for producing the same FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2010-08-03 US disclosed
US-20100016498-A1 Epoxy resin composition and cured article thereof NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2010-01-21 US disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5512565-A REDUCE CHOLESTEROL ABSORPTION IN MAMMALS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-04-30 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
US-5391571-A Cholesterol ester hydrolase inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 1995-02-21 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed
WO-1993013067-A1 4-SUBSTITUTED PIPERIDINECARBOXYLIC ACID ESTERS: INHIBITION OF CHOLESTEROL ABSORPTION AMERICAN HOME PRODUCTS CORPORATION (US) 1993-07-08 WO disclosed
US-5169844-A Enzyme inhibitor, anticholesterol and antilipemic agent AMERICAN HOME PRODUCTS CORPORATION (US) 1992-12-08 US disclosed
EP-0428385-A1 Cholesterol ester hydrolase inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 1991-05-22 EP disclosed
EP-0356797-A2 Substituted pyridines, process for their preparation and their use in insecticides BAYER AG (DE) 1990-03-07 EP disclosed
US-4855279-A SENSITIZER EXCELLENT IN THERMAL RESPONSE PROPERTIES AND SENSI TIVITY MITSUBISHI PAPER MILLS, LIMITED (JP) 1989-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 LTA4H 1523/4885ESR2 4337/4885MEN1 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.