Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046464 | 0.85 | KMT2A (0.43) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL2366873 | 0.85 | TLR8 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL23831996 | 0.84 | CYP3A4 (0.37) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL11097121 | 0.81 | ALDH1A1 (0.33) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL3414509 | 0.80 | NMT1 (0.35) | ALDH1A1KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL3416775 | 0.80 | KMT2A (0.40) | ALDH1A1HPGDCYP1A2CYP2C9KMT2A | |
| SCHEMBL320021 | 0.78 | TSHR (0.48) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL7643608 | 0.77 | TSHR (0.46) | ALDH1A1TSHRCYP3A4HPGDCYP1A2 | |
| SCHEMBL4053905 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL23647915 | 0.75 | ERN1 (0.36) | ALDH1A1TSHRCYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11440989-B2 | Application of Mannich base in flame-retardant polyurethane material | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2022-09-13 | — | — | US | disclosed |
| US-11401375-B2 | Flame-retardant polyether polyol as well as preparation method and application thereof | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2022-08-02 | — | — | US | disclosed |
| US-20200283562-A1 | APPLICATION OF MANNICH BASE IN FLAME-RETARDANT POLYURETHANE MATERIAL | JIAHUA CHEMICALS INC. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-20200283573-A1 | FLAME-RETARDANT POLYETHER POLYOL AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-20200283573-A1 | FLAME-RETARDANT POLYETHER POLYOL AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF | JIAHUA SCIENCE & TECHNOLOGY DEVELOPMENT (SHANGHAI) LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
| US-20200283562-A1 | APPLICATION OF MANNICH BASE IN FLAME-RETARDANT POLYURETHANE MATERIAL | JIAHUA CHEMICALS INC. (CN) | 2020-09-10 | — | — | US | disclosed |
| CN-109467690-A | A kind of flame-retardant polyether glycol and its preparation method and application | 佳化化学科技发展（上海）有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456472-A | A kind of application of Mannich base in Flame retardant polyurethane material | 佳化化学科技发展（上海）有限公司 | 2019-03-12 | — | — | CN | disclosed |
| EP-2265616-A1 | FURO-AND THIENO[3,2-C]PYRIDINES | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009100282-A1 | FURO-AND THIENO[3,2-C] PYRIDINES | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440989-B2 | Application of Mannich base in flame-retardant polyurethane material | FBL, HNRNPUL2, HNRNPUL1 | ALDH1A1 1170/4885TSHR 2890/4885HSD17B10 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.