Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415768 | 0.85 | ALDH1A1 (0.43) | TLR8ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL18242334 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL1926900 | 0.76 | TAAR1 (0.54) | TLR8TSHRHSD17B10CYP3A4CYP1A2 | |
| SCHEMBL11239663 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL8106157 | 0.76 | NPC1 (0.43) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL6130331 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL18242042 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL6136788 | 0.74 | CYP11B1 (0.38) | TLR8SIRT2KDM4EPOLB | |
| SCHEMBL1589651 | 0.74 | GPR17 (0.46) | — | |
| SCHEMBL320021 | 0.74 | TSHR (0.48) | ALDH1A1TSHRHSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364293-B1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| EP-2364293-B1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| EP-2364293-A2 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010063700-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010063700-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | CASP1, CASP14, CD14 | TLR8 81/4885ALDH1A1 390/4885TSHR 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.