Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL29087270 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL28552827 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL31197285 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL932243 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1653064 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1159891 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL5559315 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL18045516 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1263267 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL8058033 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119233757-A | Agricultural composition | 奥罗农业欧洲股份公司 | 2024-12-31 | — | — | CN | claimed |
| CN-116963511-A | Perovskite solar cell modified by phenylphosphoric acid and preparation method thereof | 南通大学 | 2023-10-27 | — | — | CN | claimed |
| CN-112912386-B | Cell penetrating peptides based on influenza virus M2 proteins | 中国医学科学院基础医学研究所 | 2023-10-20 | — | — | CN | claimed |
| US-11732217-B2 | Cleaning solution composition and cleaning method using the same | KCTECH CO., LTD. (KR) | 2023-08-22 | — | — | US | claimed |
| CN-116102760-A | Production method of flame-retardant and easily-infiltrated CPP film | 宁波瑞成包装材料有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-115872731-A | Method for eliminating layering and step effect of photocuring 3D printing ceramic | 深圳大学 | 2023-03-31 | — | — | CN | claimed |
| CN-114805247-A | Method for synthesizing alpha-epoxy pinane by using alpha-pinene | 上海交通大学 | 2022-07-29 | — | — | CN | claimed |
| CN-110975915-B | Preparation method and application of catalyst for preparing methyl heptanone by one-step method | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| US-20220056373-A1 | CLEANING LIQUID COMPOSITION AND CLEANING METHOD USING SAME | KCTECH CO., LTD. (KR) | 2022-02-24 | — | — | US | claimed |
| US-20220025299-A1 | CLEANING SOLUTION COMPOSITION AND CLEANING METHOD USING THE SAME | KCTECH CO., LTD. (KR) | 2022-01-27 | — | — | US | claimed |
| US-8100020-B2 | Compliant and wireless health monitoring sensors for composite structures | Lumimove, Inc., a Missouri Corporation (US) | 2012-01-24 | — | — | US | claimed |
| JP-2011525240-A | — | — | 2011-09-15 | — | — | JP | claimed |
| WO-2011101857-A2 | MULTIFUNCTIONAL TEXTILE | KHANDELWAL, SANJEEV (IN) | 2011-08-25 | — | — | WO | claimed |
| EP-2297559-A2 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | Lumimove, Inc., Dba Crosslink (US) | 2011-03-23 | — | — | EP | claimed |
| US-20100095781-A1 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | LUMIMOVE, INC., D/B/A CROSSLINK (US) | 2010-04-22 | — | — | US | claimed |
| WO-2009155367-A2 | COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES | LUMIMOVE, INC., D/B/A CROSSLINK (US) | 2009-12-23 | — | — | WO | claimed |
| US-6129927-A | Plant care product applicable by spray methods and process for the manufacture of said product | FOOD MACHINERY ESPANOLA, S.A. (ES) | 2000-10-10 | — | — | US | claimed |
| US-4940787-A | Process for the carbonylation of acetylenic unsaturated compounds | SHELL OIL COMPANY (US) | 1990-07-10 | — | — | US | claimed |
| EP-0271144-A2 | Process for the carbonylation of acetylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | claimed |
| US-4578156-A | Electrolytes for electrochemically treating metal plates | AMERICAN HOECHST CORPORATION (US) | 1986-03-25 | — | — | US | claimed |