Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL29087270 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL341618 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL28552827 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL31197285 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1653064 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1159891 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL5559315 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL18045516 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL1263267 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Benzene SCHEMBL8058033 | 1.00 | CA2 (0.47) | CA2CA4CA5ASRCCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708810-A | Modified polyphenyl ether material, foaming beads thereof and foaming molded body | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119194466-A | Bismuth-based electrochemical reduction catalyst and preparation method and application thereof | 北京化工大学 | 2024-12-27 | — | — | CN | claimed |
| CN-118812916-A | Infrared absorber, laser marking aid and polyamide material with laser marking function | 江苏博云塑业股份有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-115627064-B | Antistatic PC/ABS composition, and preparation method and application thereof | 天津金发新材料有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117120522-A | Polyimide film for graphite sheet and graphite sheet produced therefrom | 聚酰亚胺先端材料有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-116722219-A | Functional lithium ion battery electrolyte with extremely high stability and preparation method thereof | 四川大学 | 2023-09-08 | — | — | CN | claimed |
| CN-219525407-U | Bisphenol A diphenyl diphosphate serialization apparatus for producing | 国蓝新材料技术研发(山东)有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-11685830-B2 | Flame retardant resin composition and flame retardant resin molded article manufactured therefrom | LG CHEM, LTD. (KR) | 2023-06-27 | — | — | US | claimed |
| EP-3778748-B1 | NONHALOGEN FLAME RETARDANT RESIN COMPOSITION AND FLAME RETARDANT RESIN MOLDED ARTICLE MANUFACTURED THEREFROM | LG CHEMICAL LTD (KR) | 2023-04-26 | — | — | EP | claimed |
| CN-115627064-A | Antistatic PC/ABS composition and preparation method and application thereof | 天津金发新材料有限公司 | 2023-01-20 | — | — | CN | claimed |
| US-20210246306-A1 | NONHALOGEN FLAME RETARDANT RESIN COMPOSITION AND FLAME RETARDANT RESIN MOLDED ARTICLE MANUFACTURED THEREFROM | LG CHEM, LTD. (KR) | 2021-08-12 | — | — | US | claimed |
| EP-3778748-A1 | NON-HALOGEN FLAME-RETARDANT RESIN COMPOSITION AND FLAME-RETARDANT RESIN MOLDED ARTICLE PREPARED THEREFROM | LG CHEM, LTD. (KR) | 2021-02-17 | — | — | EP | claimed |
| CN-112119116-A | Non-halogen flame-retardant resin composition and flame-retardant resin molded article made therefrom | 株式会社LG化学 | 2020-12-22 | — | — | CN | claimed |
| CN-109233046-B | Preparation method of phosphorus-containing flame-retardant polyethylene cable material | 兰州理工大学 | 2020-12-08 | — | — | CN | claimed |
| CN-111117054-A | Low-smoke halogen-free flame-retardant B1-grade polyolefin cable sheath material and preparation method thereof | 安徽蒙特尔电缆集团有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-107075202-A | Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings | 弗劳恩霍弗应用研究促进协会 | 2017-08-18 | — | — | CN | claimed |
| CN-107001698-A | Phosphorous organic epoxide acid imide is used as flame retardant of plastic agent and/or the purposes of stabilizer, fire-retardant and/or stable plastics composite, its preparation method, molded item, paint and coating | 弗劳恩霍弗应用研究促进协会 | 2017-08-01 | — | — | CN | claimed |
| US-20110112226-A1 | Products with improved flame resistance | BAYER MATERIALSCIENCE AG (DE) | 2011-05-12 | — | — | US | claimed |
| EP-0985702-B1 | Flame retardant dispersion composition | CONSORTIUM ELEKTROCHEM IND (DE) | 2002-11-27 | — | — | EP | claimed |
| US-6111002-A | Flame-retardant dispersion composition | WACKER-CHEMIE GMBH (DE) | 2000-08-29 | — | — | US | claimed |