Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23641954 | 1.00 | LMNA (0.70) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL5279915 | 0.97 | LMNA (0.74) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL30352536 | 0.87 | LMNA (0.93) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9733197 | 0.87 | LMNA (0.93) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL892987 | 0.84 | LMNA (1.00) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL6081619 | 0.81 | LMNA (0.93) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9093331 | 0.81 | LMNA (0.93) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL3757253 | 0.81 | LMNA (0.93) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9432326 | 0.79 | LMNA (0.48) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL13296397 | 0.78 | POLB (0.49) | LMNACHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4105203-A1 | SPIRO-CONDENSED INDOLE COMPOUNDS AS EHMT2 INHIBITORS | Epizyme Inc (US) | 2022-12-21 | — | — | EP | disclosed |
| EP-1389216-B1 | AVERMECTINS SUBSTITUTED IN THE 4\"-POSITION HAVING PESTICIDAL PROPERTIES | MERIAL INC (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-2265569-A2 | NITRILE COMPOUND AND ITS USE FOR CONTROL OF ARTHROPOD PEST | Sumitomo Chemical Company, Limited (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |
| US-7605134-B2 | Pesticides | MERIAL LIMITED (US) | 2009-10-20 | — | — | US | disclosed |
| WO-2009116687-A2 | NITRILE COMPOUND AND ITS USE FOR CONTROL OF ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-24 | — | — | WO | disclosed |