Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21421564 | 0.84 | LMNA (0.44) | POLBNPSR1LMNAATMALDH1A1 | |
| SCHEMBL5279915 | 0.80 | LMNA (0.74) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL19251054 | 0.79 | NPSR1 (0.50) | POLBNPSR1LMNAATMNOS3 | |
| SCHEMBL23641954 | 0.78 | LMNA (0.70) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3416239 | 0.78 | LMNA (0.70) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL13956300 | 0.78 | NPSR1 (0.48) | POLBNPSR1LMNAATMNOS3 | |
| SCHEMBL8063896 | 0.76 | NPSR1 (0.47) | POLBNPSR1LMNAATMNOS3 | |
| SCHEMBL14979150 | 0.76 | LMNA (0.41) | NPSR1LMNAALDH1A1CHRM1CHRM2 | |
| SCHEMBL7510661 | 0.74 | LMNA (0.44) | LMNACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL13296359 | 0.74 | LMNA (0.44) | POLBLMNACHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |
| US-7605134-B2 | Pesticides | MERIAL LIMITED (US) | 2009-10-20 | — | — | US | disclosed |