Phenylethylmalonamide

Phenylethylmalonamide

SCHEMBL341785

CCC(C(N)=O)(C(N)=O)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
HTT P42858 1/20 0.46
KCNN4 O15554 7/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
KIF11 P52732 2/20 0.44
CYP2D6 P10635 2/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
CYP1A2 P05177 2/20 0.41
DRD2 P14416 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylethylmalonamide SCHEMBL29755357 0.98 MAPT (0.53) MAPTKMT2AHTTKCNN4CYP2C19
Phenylethylmalonamide - SCHEMBL7828223 0.92 KMT2A (0.52) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL15945879 0.84 PIN1 (0.47) MAPTKMT2AKCNN4CYP2D6CHRM2
SCHEMBL2291949 0.83 CYP2C19 (0.47) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL29467999 0.82 NPC1 (0.42) MAPTKMT2AKIF11LMNACYP1A2
SCHEMBL21269854 0.81 CYP2C19 (0.45) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL21268799 0.81 CYP2C19 (0.45) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL21269982 0.81 CYP2C19 (0.45) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL28875698 0.81 CYP2C19 (0.45) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL28316424 0.81 CYP2C19 (0.45) MAPTKMT2AHTTKCNN4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1051 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122085568-A Ion gel electrolyte composition capable of being subjected to room-temperature in-situ spontaneous polymerization, electrolyte and application 2026-05-26 CN claimed
US-12630726-B2 Manufacturing art paints from discarded materials Encore Artistic Solutions, Inc 2026-05-19 US claimed
US-12606723-B2 Thermosetting resin composition, semiconductor device and electrical/electronic component KYOCERA CORPORATION (JP) 2026-04-21 US claimed
EP-3962413-B1 A NEW ADVANCED FORMULATION FOR HYDROPHOBIC INTRAOCULAR LENSES AND THEIR PRODUCTION METHOD VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI (TR) 2026-04-08 EP claimed
EP-4716528-A1 PREPARATION OF TOLERIZING NANOPARTICLES FOR THE TREATMENT OF PRIMARY BILIARY CHOLANGITIS Cour Pharmaceuticals Development Company Inc. (US) 2026-04-01 EP claimed
EP-4687970-A1 TOLERIZING IMMUNE MODIFYING NANOPARTICLES FOR MYASTHENIA GRAVIS TREATMENT Cour Pharmaceuticals Development Company Inc. (US) 2026-02-11 EP claimed
US-20260028489-A1 SUPPORTED POLYMERIZATION INHIBITORS AND THEIR USE IN CURABLE COMPOSITIONS FOR 3D PRINTING ALIGN TECHNOLOGY INC (US) 2026-01-29 US claimed
US-20260027276-A1 APPARATUS FOR REMOVING CHEMOTHERAPY COMPOUNDS FROM BLOOD DELCATH SYSTEMS, INC. (US) 2026-01-29 US claimed
EP-4674873-A1 CYCLIC OLIGOMER, METHOD FOR PRODUCING SAME, COMPOUNDING MATERIAL AND COMPOSITE MATERIAL COMPRISING SAME, AND MEDICAL ARTICLE SURFACE-MODIFIED OR SURFACE-TREATED THEREWITH Korea Institute of Science and Technology (KR) 2026-01-07 EP claimed
WO-2025198684-A9 BaTiO3 NANOCRYSTALS AND NANOCOMPOSITES PIXELLIGENT TECHNOLOGIES LLC (US) 2025-11-27 WO claimed
US-20060251649-A1 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate NEUREN PHARMACEUTICALS LIMITED (NZ) 2006-11-09 US claimed
EP-1718971-A2 SYSTEM AND METHOD FOR REAL-TIME DIAGNOSIS, TREATMENT, AND THERAPEUTIC DRUG MONITORING UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2006-11-08 EP claimed
WO-2005098429-A2 SYSTEM AND METHOD FOR REAL-TIME DIAGNOSIS, TREATMENT, AND THERAPEUTIC DRUG MONITORING UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-10-20 WO claimed
US-20050233459-A1 Marker detection method and apparatus to monitor drug compliance UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2005-10-20 US claimed
US-20050054942-A1 System and method for therapeutic drug monitoring UNIVERSITY OF FLORIDA 2005-03-10 US claimed
US-6010715-A SUSTAINED DRUG RELEASE; MONOLITHIC CARRIER BERTEK, INC. (US) 2000-01-04 US claimed
EP-0563507-B1 Transdermal patch incorporating a polymer film incorporated with an active agent BERTEK INC (US) 1998-05-27 EP claimed
US-5679373-A MELT-BLENDING THERMOPLASTIC MATRIX; IMPERMEABLE BACKING; LAMINATION WITHOUT ADHESIVE; CONTROLLED RELEASE BERTEK, INC. (US) 1997-10-21 US claimed
US-5662926-A SOLVENT FREE BERTEK, INC. (US) 1997-09-02 US claimed
EP-0563507-A1 Transdermal patch incorporating a polymer film incorporated with an active agent MLI ACQUISITION CORP. II (US) 1993-10-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630726-B2 Manufacturing art paints from discarded materials PKM, KMT5B, SETDB1 MAPT 41/4885KMT2A 62/4885HTT 688/4885
US-20260027276-A1 APPARATUS FOR REMOVING CHEMOTHERAPY COMPOUNDS FROM BLOOD HCCS, F8, ABCC1 MAPT 3806/4885KMT2A 2157/4885HTT 4045/4885
US-20060251649-A1 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate GRM2, GRIN2C, GRIN2A MAPT 2325/4885KMT2A 157/4885HTT 3797/4885
US-12606723-B2 Thermosetting resin composition, semiconductor device and electrical/electronic component RPS3A, SEM1, DAP3 MAPT 333/4885KMT2A 1835/4885HTT 1550/4885
US-20260028489-A1 SUPPORTED POLYMERIZATION INHIBITORS AND THEIR USE IN CURABLE COMPOSITIONS FOR 3D PRINTING ILK, MTCL3, MARK3 MAPT 100/4885KMT2A 564/4885HTT 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.