Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169724 | 0.97 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| Iodide SCHEMBL11713121 | 0.97 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| Bromide SCHEMBL11714912 | 0.97 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| SCHEMBL3418278 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10MAPTCYP3A4 | |
| SCHEMBL11142745 | 0.75 | PARP1 (0.63) | ALDH1A1KDM4EHSD17B10MAPTTDP1 | |
| SCHEMBL4957425 | 0.69 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| SCHEMBL19451945 | 0.68 | KIF11 (0.42) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| Aminacrine SCHEMBL1040669 | 0.67 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10MAPTGPR3 | |
| SCHEMBL239920 | 0.67 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10PSMB8MAPT | |
| 2-Mercaptobenzimidazole SCHEMBL29360590 | 0.67 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10PSMB8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841060-A1 | METHODS FOR THE DEGRADATION OF SF6 | Westfälische Wilhelms-Universität Münster (DE) | 2021-06-30 | — | — | EP | claimed |
| WO-2019077086-A1 | METHODS FOR THE DEGRADATION OF SF6 | Westfälische Wilhelms-Universität Münster (DE) | 2019-04-25 | — | — | WO | claimed |
| US-11472813-B2 | OX2R compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-10-18 | — | — | US | disclosed |
| WO-2022117051-A1 | MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2022-06-09 | — | — | WO | disclosed |
| EP-3841060-A1 | METHODS FOR THE DEGRADATION OF SF6 | Westfälische Wilhelms-Universität Münster (DE) | 2021-06-30 | — | — | EP | disclosed |
| US-20210093717-A1 | BENZAMIDE AND ACTIVE COMPOUND COMPOSITIONS AND METHODS OF USE | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2021-04-01 | — | — | US | disclosed |
| US-10927083-B2 | Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase | DUKE UNIVERSITY (US) | 2021-02-23 | — | — | US | disclosed |
| US-10881733-B2 | Benzamide and active compound compositions and methods of use | TRANSLATIONAL DRUG DEVELOPMENT, LLC (US) | 2021-01-05 | — | — | US | disclosed |
| US-10807966-B2 | Heterocyclic compounds as kinase inhibitors | TRANSLATIONAL DRUG DEVELOPMENT, LLC (US) | 2020-10-20 | — | — | US | disclosed |
| US-10780080-B2 | Benzamide and active compound compositions and methods of use | TRANSLATIONAL DRUG DEVELOPMENT, LLC (US) | 2020-09-22 | — | — | US | disclosed |
| US-20200255448-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | TRANSLATIONAL DRUG DEVELOPMENT, LLC | 2020-08-13 | — | — | US | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050004197-A1 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| US-20040242627-A1 | 2-Iminoimidazole derivatives (1) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1394152-A1 | 2-IMINOIMIDAZOLE DERIVATIVES (1) | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1391456-A1 | 2-IMINOIMIDAZOLE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-4355004-A | HYPOGLYCEMIC ACTIVITY | BEECHAM GROUP LIMITED (GB) | 1982-10-19 | — | — | US | disclosed |
| EP-0028883-A2 | Benzimidazoline derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004197-A1 | 2-iminoimidazole derivatives (2) | H1-2, H1-3, H1-4 | ALDH1A1 417/4885KDM4E 2817/4885HSD17B10 650/4885 |
| US-10807966-B2 | Heterocyclic compounds as kinase inhibitors | MAP3K1, MAP3K20, MAP3K5 | ALDH1A1 2699/4885KDM4E 849/4885HSD17B10 2886/4885 |
| US-20210093717-A1 | BENZAMIDE AND ACTIVE COMPOUND COMPOSITIONS AND METHODS OF USE | CD274, PDCD1, PDCD1LG2 | ALDH1A1 911/4885KDM4E 113/4885HSD17B10 4251/4885 |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | ALDH1A1 443/4885KDM4E 3161/4885HSD17B10 1858/4885 |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | ALDH1A1 437/4885KDM4E 3132/4885HSD17B10 1874/4885 |
| US-10927083-B2 | Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase | TAB1, TGFBR1, CHUK | ALDH1A1 2581/4885KDM4E 954/4885HSD17B10 3788/4885 |
| US-20040242627-A1 | 2-Iminoimidazole derivatives (1) | H1-2, H1-0, H1-3 | ALDH1A1 165/4885KDM4E 1039/4885HSD17B10 1236/4885 |
| US-10881733-B2 | Benzamide and active compound compositions and methods of use | PDCD1, CD274, PDCD1LG2 | ALDH1A1 880/4885KDM4E 75/4885HSD17B10 4230/4885 |
| US-11472813-B2 | OX2R compounds | HCRTR2, HCRTR1, OXTR | ALDH1A1 3475/4885KDM4E 1812/4885HSD17B10 1507/4885 |
| US-20200255448-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | MAP3K1, MAP3K20, MAP3K5 | ALDH1A1 2699/4885KDM4E 849/4885HSD17B10 2886/4885 |
| US-10780080-B2 | Benzamide and active compound compositions and methods of use | TNFRSF1A, TNFRSF9, CD40 | ALDH1A1 1502/4885KDM4E 2443/4885HSD17B10 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.