SCHEMBL341832

SCHEMBL341832

c1ccc(P(c2ccccc2)c2cc3ccccc3c(-c3cccc4ccccc34)c2P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.40
CES1 P23141 1/20 0.36
MCL1 Q07820 2/20 0.35
ACMSD Q8TDX5 1/20 0.35
SOS1 Q07889 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DHFR P00374 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ALPL P05186 1/20 0.33
GAA P10253 1/20 0.33
TYMP P19971 1/20 0.33
GSK3B P49841 1/20 0.33
ADK P55263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350512 1.00 GPR84 (0.40) GPR84CES1MCL1ACMSDSOS1
Hydrochloric Acid SCHEMBL3221967 0.97 GPR84 (0.38) GPR84CES1MCL1ACMSDSOS1
SCHEMBL29479218 0.94 GPR84 (0.36) GPR84CES1MCL1ACMSDSOS1
SCHEMBL30616090 0.89 DHFR (0.37) GPR84CES1ALDH1A1HPGDHSD17B10
SCHEMBL2424517 0.89 DHFR (0.37) GPR84CES1ALDH1A1HPGDHSD17B10
SCHEMBL3629384 0.89 DHFR (0.37) GPR84CES1ALDH1A1HPGDHIF1A
SCHEMBL6012740 0.87 DHFR (0.38) GPR84CES1ALDH1A1HPGDHIF1A
SCHEMBL29743080 0.87 DHFR (0.38) GPR84CES1ALDH1A1HPGDHIF1A
SCHEMBL16990163 0.86 GPR84 (0.32) GPR84
SCHEMBL30894435 0.85 GPR84 (0.39) GPR84CES1ALDH1A1L3MBTL1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1043 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073445-B Organic luminescent material based on selenohexanthrone and preparation method and application thereof 中国科学院长春应用化学研究所 2024-02-13 CN claimed
CN-117534655-A Quinolone compound and preparation method and application thereof 复旦大学 2024-02-09 CN claimed
CN-117050096-A Preparation method of risperidone 杭州诺澳生物医药科技有限公司 2023-11-14 CN claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP claimed
WO-2023198562-A1 MOLECULARLY IMPRINTED POLYMER UNIVERSITEIT MAASTRICHT (NL) 2023-10-19 WO claimed
CN-111808041-B Difluoroalkyl aryl oxazolidinone compound and preparation method thereof 成都大学 2023-02-28 CN claimed
CN-115403516-A 3,4, 5-trisubstituted benzene ring-containing aromatic heterocyclic compound, pharmaceutical composition, preparation method and application thereof 河南省儿童医院郑州儿童医院 2022-11-29 CN claimed
CN-111825523-B Hydroxycitronellol and preparation method thereof 万华化学集团股份有限公司 2022-11-08 CN claimed
CN-115073445-A Organic luminescent material based on selenium heteroanthrone and preparation method and application thereof 中国科学院长春应用化学研究所 2022-09-20 CN claimed
CN-112794851-B 3- (pyridine-3-yl) -7-azaindole derivative PI3K delta inhibitor and preparation method and application thereof 复旦大学 2022-08-23 CN claimed
EP-1532100-A1 METHOD FOR THE ENANTIOSELECTIVE HYDROGENATION OF AMINO ALCOHOLS MERCK PATENT GmbH (DE) 2005-05-25 EP claimed
WO-2005013985-A1 TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED CONDITIONS MERCK SHARP & DOHME LIMITED (GB) 2005-02-17 WO claimed
WO-2004020389-A1 METHOD FOR THE ENANTIOSELECTIVE HYDROGENATION OF AMINO ALCOHOLS MERCK PATENT GMBH (DE) 2004-03-11 WO claimed
WO-2001021670-A1 PALLADIUM (II) CATALYZED POLYMERIZATION OF NORBORNENE AND ACRYLATES THE PENN STATE RESEARCH FOUNDATION (US) 2001-03-29 WO claimed
EP-0846676-B1 Process for the preparation of aromatic amines from aryl chlorides AXIVA GMBH (DE) 2001-02-07 EP claimed
US-5831128-A Synthesis of aromatic amines from chloroamatics HOECHST AKTIENGESELLSCHAFT (DE) 1998-11-03 US claimed
EP-0846676-A1 Process for the preparation of aromatic amines from aryl chlorides HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-10 EP claimed
US-5627256-A STABILIZER BAYER AG (DE) 1997-05-06 US claimed
US-RE35292-E CONCENTRATING BY PASSING THROUGH AROMATIC POLYAMIDE SEMIPERMEABLE MEMBRANE; DIALYSIS, ULTRAFILTRATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-09 US claimed
US-5174899-A Ultrafiltration or dialysis with semipermeable aromatic polyamide membranes HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-29 US claimed