SCHEMBL3629384

SCHEMBL3629384

Cc1cccc(P(c2cccc(C)c2)c2cc3ccccc3c(-c3cccc4ccccc34)c2P(c2cccc(C)c2)c2cccc(C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
GPR84 Q9NQS5 1/20 0.34
CES1 P23141 1/20 0.33
GSK3B P49841 1/20 0.33
ADK P55263 1/20 0.33
CYP1A2 P05177 4/20 0.33
CYP2A6 P11509 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ENPP1 P22413 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
FLT3 P36888 1/20 0.31
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29743080 0.90 DHFR (0.38) DHFRMAOAMAOBGPR84CES1
SCHEMBL6012740 0.90 DHFR (0.38) DHFRMAOAMAOBGPR84CES1
SCHEMBL30616090 0.89 DHFR (0.37) DHFRMAOAMAOBGPR84CES1
SCHEMBL2424517 0.89 DHFR (0.37) DHFRMAOAMAOBGPR84CES1
SCHEMBL29350512 0.89 GPR84 (0.40) DHFRGPR84CES1GSK3BADK
SCHEMBL341832 0.89 GPR84 (0.40) DHFRGPR84CES1GSK3BADK
Hydrochloric Acid SCHEMBL3221967 0.86 GPR84 (0.38) DHFRGPR84CES1GSK3BADK
SCHEMBL8961365 0.85 DHFR (0.39) DHFRMAOAMAOBGPR84GSK3B
SCHEMBL29479218 0.84 GPR84 (0.36) DHFRGPR84CES1GSK3BADK
SCHEMBL30894421 0.82 DHFR (0.34) DHFRGPR84CES1GSK3BADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611819-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND Takasago International Corporation (JP) 2013-07-10 EP disclosed
WO-2012029970-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-03-08 WO disclosed
EP-2158154-A1 METHOD FOR THE PRODUCTION OF HYDROGEN FROM AMMONIA BORANE Kanata Chemical Technologies Inc. (CA) 2010-03-03 EP disclosed
WO-2008141439-A1 METHOD FOR THE PRODUCTION OF HYDROGEN FROM AMMONIA BORANE KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2008-11-27 WO disclosed
EP-0403188-A2 A compound of 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl and catalytic complexes thereof Takasago International Corporation (JP) 1990-12-19 EP disclosed