SCHEMBL3418397

SCHEMBL3418397

O=C1C=C(O)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3737564 0.74
SCHEMBL8993949 0.67
SCHEMBL328120 0.67
SCHEMBL6781313 0.65
SCHEMBL7999251 0.65
SCHEMBL471793 0.63
SCHEMBL6470821 0.62
SCHEMBL22849334 0.60
SCHEMBL18850100 0.59
SCHEMBL31324313 0.59 MAPT (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603148-A Pharmacokinetic enhancement of difunctional chelates and uses thereof 探针技术开发及商业化中心 2024-02-27 CN claimed
US-20250326777-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) 2025-10-23 US disclosed
EP-4605374-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF Hepaitech (Beijing) Biopharma Technology Co., Ltd. (CN) 2025-08-27 EP disclosed
CN-119156135-A Methods and compositions for controlling pests on soybeans 环球化学股份有限公司 2024-12-17 CN disclosed
CN-113939509-B Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2024-11-29 CN disclosed
CN-112679467-B Heterocyclic substituted bicyclic ring Azole pesticides FMC公司 2024-11-01 CN disclosed
CN-112752753-B Pesticidal mixtures comprising indazole compounds FMC公司 2024-09-17 CN disclosed
WO-2024174995-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) 2024-08-29 WO disclosed
CN-112608300-B Heterocyclic substituted bicyclic azole pesticides FMC公司 2024-04-26 CN disclosed
WO-2024083210-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) 2024-04-25 WO disclosed
WO-2006021340-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F.HOFFMANN-LA ROCHE AG (CH) 2006-03-02 WO disclosed
US-20060040927-A1 Heterocyclic antiviral compounds ROCHE PALO ALTO LLC 2006-02-23 US disclosed
WO-2004108683-A1 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-16 WO disclosed
EP-0358128-B1 Process for the preparation of 5-alkyltetramic acids LONZA AG (CH) 1995-06-28 EP disclosed
US-5420155-A Treatment of nervous system disorders with derivatives of 4-hydroxy-2-(1H)-pyrrolones such as strokes, antiischemic agents or cardiovascular disorders MERCK SHARP & DOHME LTD. (GB) 1995-05-30 US disclosed
US-5420155-A Treatment of nervous system disorders with derivatives of 4-hydroxy-2-(1H)-pyrrolones such as strokes, antiischemic agents or cardiovascular disorders MERCK SHARP & DOHME LTD. (GB) 1995-05-30 US disclosed
US-5008402-A Reacting a 3-pyrrolin-2-one with an aldehyde or ketone; hydrogenating LONZA LTD. (CH) 1991-04-16 US disclosed
US-4983743-A Statine chemical intermediates LONZA, LTD. (CH) 1991-01-08 US disclosed
US-4925868-A CARDIOVASCULAR DISORDERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-05-15 US disclosed
EP-0358128-A2 Process for the preparation of 5-alkyltetramic acids LONZA AG (CH) 1990-03-14 EP disclosed