Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287232 | 0.90 | ALDH1A1 (0.60) | CRHBPCRHR2HIF1AALDH1A1TSHR | |
| SCHEMBL297617 | 0.90 | ALDH1A1 (0.60) | CRHBPCRHR2HIF1AALDH1A1TSHR | |
| SCHEMBL200188 | 0.87 | BACE1 (0.49) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL8900064 | 0.85 | BACE1 (0.47) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL17500060 | 0.82 | ESR2 (0.47) | TSHRCYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL6320034 | 0.81 | CYP1A2 (0.53) | TSHRCYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL14702266 | 0.79 | CYP2C19 (0.40) | HIF1ATSHRCYP3A4CYP2C9CYP1A2 | |
| SCHEMBL14820672 | 0.78 | CYP1A2 (0.50) | TSHRCYP3A4CYP2C9CYP1A2CYP2C19 | |
| Potassium Ion SCHEMBL3416456 | 0.78 | ALDH1A1 (0.38) | CRHBPCRHR2HIF1AALDH1A1CYP2C9 | |
| SCHEMBL5034217 | 0.78 | CYP2C19 (0.42) | TSHRCYP3A4CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896507-B | Catalyst compounds and their use | EXXONMOBIL CHEM PATENTS INC | 2012-11-28 | — | — | CN | disclosed |
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| CN-101896507-A | Catalyst compounds and their use | EXXONMOBIL CHEM PATENTS INC | 2010-11-24 | — | — | CN | disclosed |
| EP-2231715-A1 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| US-7767773-B2 | Catalyst compounds are use thereof | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767773-B2 | Catalyst compounds are use thereof | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767773-B2 | Catalyst compounds are use thereof | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7705157-B2 | Phenol-heterocyclic ligands, metal complexes, and their uses as catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705157-B2 | Phenol-heterocyclic ligands, metal complexes, and their uses as catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100048841-A1 | PHENOL-HETEROCYCLIC LIGANDS, METAL COMPLEXES, AND THEIR USES AS CATALYSTS | SYMYX SOLUTIONS, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2112173-A1 | Catalyst compounds and use thereof | ExxonMobil Chemical Patents Inc. (US) | 2009-10-28 | — | — | EP | disclosed |
| WO-2009082556-A1 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009082556-A1 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-07-31 | — | — | US | disclosed |
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-07-31 | — | — | US | disclosed |
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-07-31 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182952-A1 | Catalyst Compounds And Use Thereof | HACL2, AHCYL1, CRKL | CRHBP 3224/4885CRHR2 2147/4885HIF1A 1565/4885 |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | CRHBP 981/4885CRHR2 1337/4885HIF1A 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.