SCHEMBL6320034

SCHEMBL6320034

CC(C)(C)c1cc(-c2ccccc2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
TSHR P16473 1/20 0.53
CYP2C19 P33261 1/20 0.53
HSP90AA1 P07900 1/20 0.51
CA2 P00918 2/20 0.45
CA1 P00915 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
PTPN5 P54829 1/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
BACE1 P56817 2/20 0.42
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14820672 0.97 CYP1A2 (0.50) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL2995994 0.91 CYP3A4 (0.44) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL200188 0.89 BACE1 (0.49) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL8900064 0.87 BACE1 (0.47) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL5521853 0.86 CA2 (0.47) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL510694 0.85 CA2 (0.59) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL15890733 0.84 CYP1A2 (0.46) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL17500060 0.84 ESR2 (0.47) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL21753677 0.84 CA2 (0.57) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL14773891 0.83 TSHR (0.41) CYP1A2CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544069-B2 Method for dimerization of ethylene comprising a step for treatment of the reaction effluent IFP Energies Nouvelles (FR) 2020-01-28 US claimed
CN-104941682-B Catalyst composition and for making ethylene oligomerization at the method for 1- hexene IFP 新能源公司 2019-07-30 CN claimed
CN-109942362-A Include the steps that the ethylene dimerization method for handling reaction effluent IFP 新能源公司 2019-06-28 CN claimed
US-20190169085-A1 METHOD FOR DIMERIZATION OF ETHYLENE COMPRISING A STEP FOR TREATMENT OF THE REACTION EFFLUENT IFP Energies Nouvelles (FR) 2019-06-06 US claimed
CN-109337575-A A kind of preparation method of satellite external surface insulating moulding coating 南京悠谷知识产权服务有限公司 2019-02-15 CN claimed
CN-109212073-A The extraction and measuring method of 4 kinds of benzotriazole ultra-violet stabilizer residual quantities in dyeing waste water 胡贝贞 2019-01-15 CN claimed
US-9499455-B2 Process for the selective dimerisation of ethylene to 1-butene IFP Energies Nouvelles (FR) 2016-11-22 US claimed
US-20150273456-A1 NOVEL CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZING ETHYLENE INTO 1-HEXENE IFP Energies Nouvelles (FR) 2015-10-01 US claimed
CN-104941682-A Novel catalytic composition and process for oligomerizing ethylene into 1-hexene IFP Energies Nouvelles 2015-09-30 CN claimed
US-6903042-B2 Catalytic composition and process for oligomerizing ethylene, in particular to 1-hexene INSTITUT FRANCAIS DU PETROLE (FR) 2005-06-07 US claimed
CN-1424148-A Catalytic composition and improved method for ethylene-oligosynthetic 1-ethene INST FRANCAIS DU PETROLE (FR) 2003-06-18 CN claimed
US-12312312-B2 Process for separating out an effluent obtained from an oligomerization step IFP Energies Nouvelles (FR) 2025-05-27 US disclosed
US-20240239725-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies Nouvelles (FR) 2024-07-18 US disclosed
EP-4347542-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT IFP Energies nouvelles (FR) 2024-04-10 EP disclosed
CN-112533889-B Process for oligomerization in cascade with stirred gas-liquid reactor staged injection of ethylene IFP 新能源公司 2024-03-05 CN disclosed
US-20010023281-A1 Catalytic composition and a process for oligomerizing ethylene, in particular to 1-hexene INSTITUT FRANCAIS DU PETROLE (FR) 2001-09-20 US disclosed
US-6265620-B1 REACTING OLEFINIC COMPOUND WITH CARBON MONOXIDE AND HYDROGEN IN PRESENCE OF CATALYST CONTAINING METAL OF GROUP 8 TO 10 AND TRIVALENT ORANIC PHOSPHORUS COMPOUND TO PRODUCE ALDEHYDE MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-24 US disclosed
EP-1110930-A1 Catalytic composition and process for the oligomerisation of ethylene, to primarily 1-hexene INSTITUT FRANCAIS DU PETROLE (FR) 2001-06-27 EP disclosed
US-6031145-A A CATALYTIC COMPOSITION MIXTURE COMPRISING ONE CHROMIUM COMPOUND, ONE ARYLOXY ALUMINUM COMPOUND AND ONE HYDROCARBYL ALUMINUM COMPOUND FOR DIMERIZATION, TRIMERIZATION INSTITUT FRANCAIS DU PETROLE (FR) 2000-02-29 US disclosed
EP-0885656-A1 Catalytic composition and ethylene oligomerization, especially in 1-butene and/or 1-hexene Institut Français du Pétrole (FR) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239725-A1 METHOD FOR OLIGOMERISATION IN A REACTOR COMPRISING VARIABLE-DIAMETER ZONES, INCLUDING A STEP OF RECYCLING A PRE-COOLED SOLVENT PRPF40A, NSF, NOD2 CYP1A2 2159/4885CYP3A4 563/4885CYP2C9 1614/4885
US-20150273456-A1 NOVEL CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZING ETHYLENE INTO 1-HEXENE XRN2, XDH, SOD1 CYP1A2 487/4885CYP3A4 1038/4885CYP2C9 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.