Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71764 | 0.84 | EGLN3 (0.49) | ALDH1A1CYP1A2CYP3A4HPGDSPRKAB2 | |
| SCHEMBL3417205 | 0.84 | CYP3A4 (0.55) | ALDH1A1CYP1A2CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL3474810 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP3A4MAPTCYP2A6 | |
| SCHEMBL1759178 | 0.82 | CYP3A4 (0.57) | ALDH1A1CYP1A2CYP3A4MAPTCYP2A6 | |
| Hydrochloric Acid SCHEMBL71016 | 0.81 | CYP3A4 (0.55) | ALDH1A1CYP1A2CYP3A4MAPTCYP2A6 | |
| SCHEMBL12647964 | 0.81 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL12664226 | 0.78 | CYP3A4 (0.51) | ALDH1A1CYP1A2CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL2818771 | 0.77 | KMT2A (0.57) | ALDH1A1CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL12467859 | 0.76 | NAMPT (0.73) | CYP2C9NAMPT | |
| SCHEMBL28425920 | 0.76 | MAPT (0.48) | CYP1A2MAPTCYP2C9CYP2C19HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698557-B | Pyridine bipyrazole acylhydrazone derivative-based fluorescent probe and preparation method and application thereof | 河南理工大学 | 2020-10-02 | — | — | CN | claimed |
| CN-107698557-B | Pyridine bipyrazole acylhydrazone derivative-based fluorescent probe and preparation method and application thereof | 河南理工大学 | 2020-10-02 | — | — | CN | disclosed |
| EP-2593447-B1 | 3-PYRIDYL-HETEROARYLCARBOXAMIDE COMPOUNDS AS PESTICIDES | BAYER IP GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| US-9233951-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-9233951-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-20120094837-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROP SCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120094837-A1 | Novel Heterocyclic Compounds as Pesticides | BAYER CROP SCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| WO-2012007500-A2 | NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094837-A1 | Novel Heterocyclic Compounds as Pesticides | DDT, PTMS, ACHE | ALDH1A1 2531/4885CYP1A2 221/4885CYP3A4 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.