SCHEMBL3419802

SCHEMBL3419802

CCOc1ccc(OC(=O)Oc2ccc(OCC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.64
KMT2A Q03164 4/20 0.60
TDP1 Q9NUW8 2/20 0.60
LMNA P02545 2/20 0.60
MEN1 O00255 1/20 0.60
CYP1A2 P05177 1/20 0.60
PARP10 Q53GL7 1/20 0.59
NPC1 O15118 2/20 0.55
PLK1 P53350 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.52
LTA4H P09960 1/20 0.52
PLA2G4B P0C869 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706171 0.92 LTA4H (0.62) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL11768997 0.89 KMT2A (0.72) KMT2ALMNACYP1A2PARP10NPC1
SCHEMBL10705978 0.87 KMT2A (0.49) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL27853482 0.86 NQO1 (0.64) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL7166940 0.84 NQO1 (0.61) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL9668859 0.84 NQO1 (0.61) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL3234922 0.84 NQO1 (0.61) NQO1KMT2ATDP1LMNAMEN1
SCHEMBL10708398 0.84 THRB (0.55) LMNANPC1MAPTALDH1A1RAB9A
SCHEMBL6575501 0.83 TP53 (0.58) LMNACYP1A2NPC1TSHRLTA4H
SCHEMBL4642021 0.83 PARP10 (0.60) NQO1KMT2ATDP1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100179286-A1 POLYCARBONATE RESIN COMPOSITION TEIJIN LIMITED (JP) 2010-07-15 US disclosed
EP-2163583-A1 POLYCARBONATE RESIN COMPOSITION Teijin Limited (JP) 2010-03-17 EP disclosed
EP-1327665-B1 PROCESS FOR PRODUCING POLYCARBONATE MITSUBISHI GAS CHEMICAL CO (JP) 2009-05-27 EP disclosed
EP-2060595-A1 POLYCARBONATE HAVING PLANT-DERIVED COMPONENT AND METHOD FOR PRODUCING THE SAME Teijin Limited (JP) 2009-05-20 EP disclosed
US-6790928-B2 THERMAL STABILITY IMPROVED BY ADDITION OF PHOSPHITE; TRANSESTERIFICATION; POLYCONDENSING A CARBONIC ACID DIESTER WITH A DIHYDROXY COMPOUND IN A MOLTEN STATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-09-14 US disclosed
US-20030195326-A1 Process for producing polycarbonates MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-16 US disclosed
EP-1327665-A1 PROCESS FOR PRODUCING POLYCARBONATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-07-16 EP disclosed
EP-0760359-B1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL CO (JP) 1999-10-20 EP disclosed
US-5714627-A REACTING A DIALKYL CARBONATE WITH AN AROMATIC CARBOXYLIC ACID ARYL ESTER IN THE PRESENCE OF A CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-02-03 US disclosed
EP-0760359-A1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-03-05 EP disclosed
US-5523451-A Process for the continuous preparation of aryl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed
US-5463102-A Process for the continuous production of aryl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
US-5362901-A Process for the preparation of organic carbonates having at least one aromatic ester group BAYER AKTIENGESELLSCHAFT (DE) 1994-11-08 US disclosed
US-5344954-A Ester interchange, countercurrent flow in two-stage column reactor BAYER AKTIENGESELLSCHAFT (DE) 1994-09-06 US disclosed