SCHEMBL3419967

SCHEMBL3419967

COc1ccc(-c2ccc(-c3ccc(C#N)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
GSK3B P49841 1/20 0.54
MAPKAPK2 P49137 1/20 0.53
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
MMP3 P08254 1/20 0.52
ESR2 Q92731 1/20 0.52
KIF11 P52732 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
THRB P10828 1/20 0.50
STAT3 P40763 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
PGR P06401 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91929 1.00 MAOA (0.56) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL16604901 0.94 MAOA (0.51) MAOAMAOBGSK3BMAPKAPK2POLB
1,4-Dimethoxybenzene SCHEMBL28617696 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL103904 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL30757515 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL20282381 0.91 MAOA (0.53) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL30250275 0.91 MAOA (0.59) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL13863705 0.86 APP (0.63) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL921496 0.86 MAOA (0.56) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL28823579 0.86 ALDH1A1 (0.49) MAOAMAOBGSK3BMAPKAPK2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
EP-4431989-A1 OPTICAL FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-09-18 EP disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
WO-2022210589-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE 東ソー株式会社 2022-10-06 WO disclosed
US-20160109761-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME MERCK PATENT GMBH (DE) 2016-04-21 US disclosed
EP-2177549-B1 TRIAZINE RING-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE POLYMER COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2015-11-04 EP disclosed
US-20150092145-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME SHARP KABUSHIKI KAISHA (JP) 2015-04-02 US disclosed
US-8426037-B2 Triazine ring-containing polymer compound and organic light-emitting element using the polymer compound SHOWA DENKO K.K. (JP) 2013-04-23 US disclosed
US-7923078-B2 Light-modulating liquid-crystal element ADEKA CORPORATION (JP) 2011-04-12 US disclosed
US-20100201257-A1 TRIAZINE RING-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE POLYMER COMPOUND SHOWA DENKO K.K. (JP) 2010-08-12 US disclosed
EP-2177549-A1 TRIAZINE RING-CONTAINING POLYMER COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE POLYMER COMPOUND Showa Denko K.K. (JP) 2010-04-21 EP disclosed
US-20090279043-A1 LIGHT-MODULATING LIQUID-CRYSTAL ELEMENT ADEKA CORPORATION (JP) 2009-11-12 US disclosed