SCHEMBL91929

SCHEMBL91929

COc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
GSK3B P49841 1/20 0.54
MAPKAPK2 P49137 1/20 0.53
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
MMP3 P08254 1/20 0.52
ESR2 Q92731 1/20 0.52
KIF11 P52732 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
THRB P10828 1/20 0.50
STAT3 P40763 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
PGR P06401 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3419967 1.00 MAOA (0.56) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL16604901 0.94 MAOA (0.51) MAOAMAOBGSK3BMAPKAPK2POLB
1,4-Dimethoxybenzene SCHEMBL28617696 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL103904 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL30757515 0.93 MAOB (0.61) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL20282381 0.91 MAOA (0.53) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL30250275 0.91 MAOA (0.59) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL13863705 0.86 APP (0.63) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL921496 0.86 MAOA (0.56) MAOAMAOBGSK3BMAPKAPK2POLB
SCHEMBL28823579 0.86 ALDH1A1 (0.49) MAOAMAOBGSK3BMAPKAPK2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
EP-4431989-A1 OPTICAL FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-09-18 EP disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
CN-117157337-A Fumaric acid diester resin, film and polarizing plate 东曹株式会社 2023-12-01 CN disclosed
EP-3688000-B1 HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS ALBEMARLE GERMANY GMBH (DE) 2023-11-08 EP disclosed
WO-2023167325-A1 IMMOBILIZED PALLADIUM CATALYST AND METHOD FOR PRODUCING SAME, AND APPLICATION OF THIS CATALYST TO COUPLING REACTION 国立研究開発法人理化学研究所 2023-09-07 WO disclosed
WO-2022178427-A9 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-07-27 WO disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 US disclosed
EP-0493601-A1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-08 EP disclosed
EP-0366985-A1 Super twist liquid crystal display MERCK PATENT GmbH (DE) 1990-05-09 EP disclosed
WO-1990004622-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0238626-A4 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1989-07-26 EP disclosed
EP-0259423-A1 LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES. SECR DEFENCE BRIT (GB) 1988-03-16 EP disclosed
EP-0238626-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1987-09-30 EP disclosed
WO-1987005291-A2 LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1987-09-11 WO disclosed
US-4688900-A Light modulating material comprising a liquid crystal dispersion in a plastic matrix KENT STATE UNIVERSITY (US) 1987-08-25 US disclosed
WO-1987001822-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS KENT STATE UNIVERSITY (US) 1987-03-26 WO disclosed
US-4285829-A Liquid-crystalline dielectric MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-08-25 US disclosed