SCHEMBL34202

SCHEMBL34202

[O]c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535909 0.90 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL441299 0.88
SCHEMBL15351696 0.84
SCHEMBL3622588 0.76
SCHEMBL6842078 0.76
SCHEMBL3757312 0.76 TAS1R3 (0.33)
SCHEMBL186351 0.71 SMN1; SMN2 (0.40)
SCHEMBL42968 0.71 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1053501 0.69 SMN1; SMN2 (0.34)
SCHEMBL78210 0.68 CA1 (0.43) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5102 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113278153-B Polymer, process for producing the same and process for depolymerizing the same 北京大学 2024-07-12 CN claimed
US-20240197924-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-06-20 US claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-118064069-A Multilayer bonding material and preparation method and application thereof 上海熹贾精密技术有限公司 2024-05-24 CN claimed
CN-117989323-A Sealing assembly and preparation method thereof 上海熹贾精密技术有限公司 2024-05-07 CN claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
EP-3590919-B1 ENAMINE COMPOUND AND USE THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2024-04-24 EP claimed
CN-117903149-A Metalloporphyrin complex and application thereof in catalytic preparation of polyether 烟台大学 2024-04-19 CN claimed
US-20240115719-A1 COMPOUND OR SALT THEREOF, AND ANTIBODY OBTAINED BY USING THE SAME AJINOMOTO CO., INC. (JP) 2024-04-11 US claimed
EP-3870044-B1 COMPLEXES AND LIGANDS MASSACHUSETTS GEN HOSPITAL (US) 2024-04-10 EP claimed
EP-0225792-A2 Blends of fluoroplastics and fluoroelastomers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-16 EP claimed
US-4672106-A ANTITUMOR AGENTS Hamaoka, Toshiyuki (JP) 1987-06-09 US claimed
EP-0186576-A2 Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates MERCK & CO. INC. (US) 1986-07-02 EP claimed
EP-0161188-A2 Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency MERCK & CO. INC. (US) 1985-11-13 EP claimed
US-4487963-A Enantioselective synthesis of 4-amino-3-hydroxy-2,4-(disubstituted)pentanoic acid MERCK & CO., INC. (US) 1984-12-11 US claimed
EP-0042731-B1 LARVICIDES, INSECTICIDES, ACARICIDES AND MITICIDES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM Pfizer Limited (GB) 1984-12-05 EP claimed
EP-0042731-A1 Larvicides, insecticides, acaricides and miticides, processes for preparing them and compositions containing them Pfizer Limited (GB) 1981-12-30 EP claimed
US-4145549-A CYCLIZATION, SOLVOLYSIS SANDOZ LTD. (CH) 1979-03-20 US claimed
US-4045556-A ANTIDEPRESSANTS, PYSCHOSTIMULANTS; SILYLATION SCHWERTNER EBERHARD 1977-08-30 US claimed
US-4000139-A ERGOT ALKALOID INTERMEDIATES SANDOZ LTD. (CH) 1976-12-28 US claimed